Results 1 to 10 of about 2,280 (79)

Auricular Transcutaneous Vagus Nerve Stimulation Enhances Post-Stroke Neurological and Cognitive Recovery in Mice by Suppressing Ferroptosis Through α7 Nicotinic Acetylcholine Receptor Activation. [PDF]

CNS Neurosci Ther
We reveal that ferroptosis persists from acute to chronic phases after stroke, and auricular vagus nerve stimulation (atVNS) promotes stroke recovery by suppressing ferroptosis through α7 nicotinic acetylcholine receptor activation, providing a promising noninvasive therapeutic strategy for stroke recovery.
Gong H, Zheng F, Niu B, Wang B, Xu L, Yang Y, Wang J, Tang X, Bi Y.   +8 more
europepmc   +2 more sources

Effects of Noninvasive Cervical Vagal Nerve Stimulation on Cognitive Performance But Not Brain Activation in Healthy Adults

Neuromodulation: Technology at the Neural Interface, EarlyView., 2020
Abstract Objectives While preliminary evidence suggests that noninvasive vagal nerve stimulation (nVNS) may enhance cognition, to our knowledge, no study has directly assessed the effects of nVNS on brain function and cognitive performance in healthy individuals.
Ruth Klaming, Alan N. Simmons, Andrea D. Spadoni, Imanuel Lerman   +3 more
wiley   +1 more source

Emerging Therapeutic Strategies for Hearing Loss

Advanced Therapeutics, EarlyView.
Challenges still exist in treating hearing loss in cases of severe damage to hair cells or spiral ganglion neurons. Here, a schematic diagram of cochlear sensory hair cells and auditory nerves is presented. It is found that in normal Corti organs, hair cells have upright stereocilia at the top and auditory neurons at the base. Ototoxic drugs, noise, or
Shanying Han, Tian Shen, Weiwei He, Hao Wei, Xiaolong Zhao, Wen Yang, Chuan Bu, Xinghua Tang, Yu Zhao, Jiangang Fan   +9 more
wiley   +1 more source

Electrical Stimulation Therapy – Dedicated to the Perfect Plastic Repair

Advanced Science, EarlyView.
This review discusses various types of electrical stimulation sources and materials, delving into the roles and mechanisms of electrical stimulation therapy in plastic surgery for tissue repair. This work broadens the clinical perspective of electrical stimulation, covering diverse repair needs from bone to soft tissues, and provides insights into ...
Kexin Deng, Ruizeng Luo, Ying Chen, Xiaoqiang Liu, Yuanyin Xi, Muhammad Usman, Xupin Jiang, Zhou Li, Jiaping Zhang   +8 more
wiley   +1 more source

Implantable Self‐Powered Systems for Electrical Stimulation Medical Devices

Advanced Science, EarlyView.
In this paper, the design strategy and clinical application of ISS are discussed in depth from four aspects: the design and optimization of the energy collection module, the selection and preparation of adaptive electrode materials, the innovation of system design strategy, and the biological effect of electrical stimulation of ISS.
Xi Cui, Li Wu, Chao Zhang, Zhou Li
wiley   +1 more source

Interventional therapies for chronic heart failure: An overview of recent developments

ESC Heart Failure, Volume 12, Issue 2, Page 1081-1094, April 2025.
Abstract Heart failure (HF), the final manifestation of most cardiovascular diseases, has become a major global health concern, affecting millions of individuals. Despite basic drug treatments, patients present with high morbidity and mortality rates. However, recent advancements in interventional therapy have shown promising results in improving the ...
Bingchen Guo, Si Shi, Yutong Guo, Jie Xiong, Bo Wang, Zengxiang Dong, Dianyu Gao, Yingfeng Tu   +7 more
wiley   +1 more source

Development and Application of Polyphenols in Food: A Comprehensive Review

Food Frontiers, EarlyView.
This review provides an in‐depth analysis of functional mechanisms and research trends in the application of polyphenol in food. ABSTRACT This review provides an in‐depth analysis of functional mechanisms and research trends in the application of polyphenol in food.
Yanpei Huang, Haiming Chen, Weijun Chen, Wenxue Chen, Qiuping Zhong, Jianfei Pei, Ming Zhang, Guido R. M. M. Haenen   +7 more
wiley   +1 more source

Genetically‐targeted control of the spinal cord and peripheral nervous system

Journal of Intelligent Medicine, EarlyView.
Application of genetically‐targeted stimulation for treating diseases or injuries outside the brain. Optogenetic and chemogenetic systems have been developed for dysfunction in the cochlea, spinal cord, dorsal root ganglia (DRGs), peripheral nerves, lower urinary tract, and enteric nervous system (ENS). Created with Biorender.com.
Anakaren Romero Lozano, Victoria Koptelova, Zoya Ahmad, Huiliang (Evan) Wang   +3 more
wiley   +1 more source

Effects of Transcutaneous Auricular Vagal Nerve Stimulation on Chronic Constipation: A Multicenter, Randomized Controlled Study

United European Gastroenterology Journal, EarlyView.
ABSTRACT Objective The objective of this study was to investigate the efficacy of transcutaneous auricular vagal nerve stimulation (taVNS) in adult patients with chronic constipation. Design Consecutive patients who met the Rome IV criteria for chronic constipation were enrolled and randomly assigned to either the taVNS group or the sham‐taVNS group ...
Tangyi Liu, Zeyu Wang, Yunling Li, Xiaoyu Kang, Xiangping Wang, Gui Ren, Yong Lv, Jing Li, Yaling Liu, Shuhui Liang, Xin Wang, Xiaojun Huang, Xiaoyin Zhang, Jun Wang, Yongzhan Nie, Hui Luo, Jinbo Sun, Wei Qin, Ying Han, Yanglin Pan   +19 more
wiley   +1 more source

Two‐year outcomes of epicranial focal cortex stimulation in pharmacoresistant focal epilepsy

Epilepsia, EarlyView.
Abstract Objective This study was undertaken to report on the long‐term safety and efficacy of epicranial focal cortex stimulation (FCS) using the EASEE device as adjunctive neuromodulatory therapy in improving seizure control in adults with pharmacoresistant epilepsy originating from one predominant epileptogenic zone.
Andreas Schulze‐Bonhage, Martin Hirsch, Susanne Knake, Ann Mertens, Michael Rademacher, Elisabeth Kaufmann, Josua Kegele, Carolin Jenkner, Volker Coenen, Martin Glaser, Sergiu Groppa, Yaroslav Winter, for the EASEE Study Group   +12 more
wiley   +1 more source