Transcutaneous vagus nerve stimulation

Results 11 to 20 of about 2,280 (79)

A post hoc analysis of migraine‐associated symptoms from the phase 3 randomized, double‐blind, sham‐controlled Trial of External trigeminal nerve stimulation for the Acute treatment of Migraine (TEAM) study

Headache: The Journal of Head and Face Pain, Volume 65, Issue 5, Page 779-790, May 2025.
Abstract Background The Trial of External trigeminal nerve stimulation (eTNS) for the Acute treatment of Migraine (TEAM) study demonstrated that eTNS use during active migraine resulted in significantly higher rates of resolution of migraine‐associated most bothersome symptom (MBS) compared to sham.
Gregory A. Panza +2 more
wiley +1 more source

Learning from missteps: Potential of transcranial electrical stimulation in neuropsychological rehabilitation

Journal of Neuropsychology, EarlyView.
Abstract Transcranial electrical stimulation (tES) holds promise for neuropsychological rehabilitation by leveraging the brain's inherent plasticity to enhance cognitive and motor functions. However, early results have been variable due to oversimplified approaches.
Carlo Miniussi, Maria Concetta Pellicciari +1 more
wiley +1 more source

Enteric neuropathy and the vagus nerve: Therapeutic implications

Neurogastroenterology &Motility, EarlyView.
Abstract Enteric neuropathies are characterized by abnormalities of gut innervation, which includes the enteric nervous system, inducing severe gut dysmotility among other dysfunctions. Most of the gastrointestinal tract is innervated by the vagus nerve, the efferent branches of which have close interconnections with the enteric nervous system and ...
Bruno Bonaz
wiley +1 more source

Evidence‐based review and frontiers of migraine therapy

Neurogastroenterology &Motility, Volume 37, Issue 3, March 2025.
Abstract Background Cyclic vomiting syndrome (CVS) is identified as one of the “episodic syndromes that may be associated with migraine,” along with benign paroxysmal torticollis, benign paroxysmal vertigo, and abdominal migraine. It has been proposed that CVS and migraine may share pathophysiologic mechanisms of hypothalamic activation and altered ...
Kaitlin A. Greene, Amy A. Gelfand, Larry Charleston IV +2 more
wiley +1 more source

Treatment principles in adults and development of patient‐reported outcomes in cyclic vomiting syndrome

Neurogastroenterology &Motility, Volume 37, Issue 3, March 2025.
Roadmap to Patient‐Focused Outcome Measurement in Clinical Trials. Source: US FDA, “Patient‐Focused Drug Development: Selecting, Developing, or Modifying Fit‐for‐Purpose Clinical Outcome Assessments”, Guidance for Industry, Food and Drug Administration Staff, and Other Stakeholder.
Yaozhu J. Chen, Milan Patel, Thangam Venkatesan +2 more
wiley +1 more source

Disorders of gut–brain interaction through the lens of polyvagal theory

Neurogastroenterology &Motility, Volume 37, Issue 3, March 2025.
This paper introduces a metric, vagal efficiency (VE), that tracks a brainstem “switching” mechanism regulating blood pressure's effect on vagal control of the heart and gut. Potentially offering insights into gut–brain interaction disorders. Abstract This paper introduces a metric capable of tracking a hypothetical brainstem “switching” mechanism ...
Stephen W. Porges
wiley +1 more source

Auricular Vagus Nerve Stimulation for Gastrointestinal Disorders: Hope or Hype?

United European Gastroenterology Journal, Volume 13, Issue 2, Page 182-183, March 2025.
Daniel Keszthelyi
wiley +1 more source

Future Applications of Central Neuromodulation and Neurophysiological Testing in Cyclic Vomiting Syndrome

Neurogastroenterology &Motility, Volume 37, Issue 3, March 2025.
ABSTRACT Background Cyclic vomiting syndrome (CVS) is defined by its episodic patterning. Furthermore, CVS is associated with other episodic disorders such as migraine and epilepsy. Indeed, many of the medications that are known to be useful for prophylaxis and abortive therapy in CVS are also effective in preventing and aborting migraines and seizures.
David J. Levinthal, Braden Kuo
wiley +1 more source

Cardiac Vagal Efficiency Is Enhanced by Percutaneous Auricular Neurostimulation in Adolescents With Nausea: Moderation by Antidepressant Drug Exposure

Neurogastroenterology &Motility, Volume 37, Issue 5, May 2025.
Acute enhancement of cardiac vagal efficiency (VE) is demonstrated with active compared to sham percutaneous electrical nerve field stimulation (PENFS). This effect is not found in children chronically exposed to antidepressants with anticholinergic and serotonergic effects. Figure created in BioRender.com.
Jacek Kolacz +3 more
wiley +1 more source

Acute Cervical Vagus Nerve Stimulation Modulates Gastric Slow Waves in the Distal Rat Stomach

Neurogastroenterology &Motility, EarlyView.
Slow waves were mapped on the rat gastric serosa during acute cervical vagus nerve stimulation with three stimulation protocols. The medium and high cVNS protocols modified slow wave frequency, and slow wave propagation was temporarily disrupted during stimulation in all subjects.
Omkar N. Athavale +4 more
wiley +1 more source