ABSTRACT Background The effects of phosphodiesterase 5 (PDE5) inhibitors on the incidence of long‐term outcomes in patients with cardiovascular disease are not well understood. Objective: We studied the association between PDE5 inhibitor therapy and the incidence of adverse cardiovascular major adverse cardiovascular events (MACE) in patients ...
Sumon Roy+5 more
wiley +1 more source
A Hierarchical Short Microneedle-Cupping Dual-Amplified Patch Enables Accelerated, Uniform, Pain-Free Transdermal Delivery of Extracellular Vesicles. [PDF]
Song M+10 more
europepmc +1 more source
ABSTRACT Background Plug‐based vascular closure devices (Pb‐VCD) and suture‐based vascular closure devices (Sb‐VCD) are used for percutaneous vascular access site closure during transcatheter aortic valve replacement (TAVR). Until now, no clear superiority of either device was shown in studies comparing 18 F VCDs solely.
Tobias Lerchner+6 more
wiley +1 more source
The Impact of Drug Delivery Systems on Pharmacokinetics and Drug-Drug Interactions in Neuropsychiatric Treatment. [PDF]
Nammas M.
europepmc +1 more source
Coronary Artery Vasculopathy in a Cohort of Heart Transplant Recipients: A Single Center Experience
ABSTRACT Background Coronary allograft vasculopathy (CAV) is a significant cause of late mortality in heart transplant recipients. This study assesses the development of CAV, associated rejection rates, and the potential impact of percutaneous coronary intervention (PCI) on survival in a cohort of heart transplant patients.
Hussein Krayem+4 more
wiley +1 more source
Polymeric 3D-Printed Microneedle Arrays for Non-Transdermal Drug Delivery and Diagnostics. [PDF]
Razzaghi M.
europepmc +1 more source
ABSTRACT Background Intravascular lithotripsy (IVL) is an innovative treatment for coronary artery calcification (CAC). Aims This study aimed to compare procedural and clinical outcomes of intracoronary imaging (ICI)‐guided percutaneous coronary intervention (PCI) versus angiography‐guided PCI with IVL in patients with CAC.
Akshay A. S. Phagu+14 more
wiley +1 more source
Investigation of PVA Matrix Hydrogel Loaded with <i>Centaurea cyanus</i> Extract for Wound Dressing Applications: Morphology, Drug Release, Antibacterial Efficiency, and In Vitro Evaluation. [PDF]
Abahuni Ucar M+4 more
europepmc +1 more source
Using Shockwave Lithotripsy to Treat Severe Calcified Mitral Stenosis in a Pregnant Woman
ABSTRACT Rheumatic mitral stenosis (MS) with significant calcification presents challenges for both surgical and transcatheter interventions. Percutaneous balloon mitral valvuloplasty (PBMV) is often limited in these cases due to valve rigidity, increasing the risk of mitral regurgitation (MR).
Mhd Baraa Habib+3 more
wiley +1 more source