Results 351 to 360 of about 141,563 (385)

Transdermal iontophoresis revisited

Current Opinion in Chemical Biology, 2000
Iontophoresis evolved as a transdermal enhancement technique in the 20th century, primarily for the delivery of large and charged molecules. Significant achievements have been made in the understanding of underlying mechanisms of iontophoresis and these have contributed to the rational development of iontophoretic delivery systems. The major challenges
R, Panchagnula, O, Pillai, V B, Nair, P, Ramarao   +3 more
openaire   +2 more sources

The transdermal revolution

Drug Discovery Today, 2004
Historically, developments in transdermal drug delivery have been incremental, focusing on overcoming problems associated with the barrier properties of the skin, reducing skin irritation rates and improving the aesthetics associated with passive patch systems.
Beverley J, Thomas, Barrie C, Finnin
openaire   +2 more sources

Ultrasound‐Enhanced Transdermal Transport

Journal of Pharmaceutical Sciences, 2003
The enhancement of transdermal transport by ultrasound is reviewed. After a brief discussion of the physics of ultrasound and its medical applications, the effects of high- and low-frequency ultrasound on the transport of substances across the skin are examined.
Merino, Gustavo, Kalia, Yogeshvar, Guy, Richard H.   +2 more
openaire   +3 more sources

Transdermal gene delivery

Journal of Controlled Release
Gene delivery has revolutionized conventional medical approaches to vaccination, cancer, and autoimmune diseases. However, current gene delivery methods are limited to either intravenous administration or direct local injections, failing to achieve well biosafety, tissue targeting, drug retention, and transfection efficiency for desired therapeutic ...
Wentao, Zhang, Yunlong, Jiao, Ziru, Zhang, Yuqi, Zhang, Jicheng, Yu, Zhen, Gu   +5 more
openaire   +2 more sources

Transdermal Oxybutynin

Drugs & Aging, 2003
Oxybutynin binds to the M(3) muscarinic receptors on the detrusor muscle of the bladder, preventing acetylcholinergic activation and relaxing the muscle. The transdermal system delivers oxybutynin over a 3- to 4-day period after application to intact skin.
Lynne M, Bang, Stephanie E, Easthope, Caroline M, Perry   +2 more
openaire   +2 more sources

Nicotine Transdermal Systems

Annals of Pharmacotherapy, 1993
OBJECTIVE:To review the role of transdermal nicotine as an aid to smoking cessation.DATA SOURCES:A MEDLINE search was performed that included clinical studies published in English involving transdermal nicotine; references used in those articles were screened for additional published information.STUDY SELECTION:Published clinical trials were reviewed ...
openaire   +2 more sources

Overcoming skin barriers through advanced transdermal drug delivery approaches.

Journal of Controlled Release, 2022
Vivek Phatale, Klaudi K Vaiphei, S. Jha, Dnyaneshwar Patil, Mukta Agrawal, Amit Alexander   +5 more
semanticscholar   +1 more source

Transdermal Drug Delivery

2009
Transdermal drug delivery is a validated technology contributing significantly to global pharmaceutical care. Since 1980, impressive growth in this field has been observed with many commercial successes; importantly, a new chemical entity was recently developed and approved for transdermal administration without having first been given as an injectable
openaire   +2 more sources

Transdermal Estradiol

New England Journal of Medicine, 1986
A, Basdevant, J, Conard, B, Guy-Grand
openaire   +2 more sources

Transdermal hyoscine

Anaesthesia, 1992
L J, Murdoch, M H, Wheildon
openaire   +2 more sources