Results 71 to 80 of about 11,739,221 (306)

Transfer valve Patent [PDF]

open access: yes, 1968
Three-port transfer valve with one port open continuously suitable for manned space ...
Puccinelli, A. A., Smith, J. R., Jr.
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Fluorouracil and bevacizumab plus anakinra for patients with metastatic colorectal cancer refractory to standard therapies (IRAFU): a single-arm phase 2 study

open access: yesOncoImmunology, 2018
In preclinical models, IL-1β inhibition could enhance the efficacy of fluorouracil (5-FU). In this phase 2 study, we assessed the activity and safety of 5-FU plus bevacizumab and anakinra (an IL-1β and α inhibitor) in patients with metastatic colorectal (
Nicolas Isambert   +12 more
doaj   +1 more source

Heat transfer device [PDF]

open access: yes, 1974
A heat transfer device is characterized by an hermetically sealed tubular housing including a tubular shell terminating in spaced end plates, and a tubular mesh wick concentrically arranged and operatively supported within said housing.
Kalkbrenner, R. W.
core   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

“Transfer Talk” in Talk about Writing in Progress: Two Propositions about Transfer of Learning [PDF]

open access: yes, 2019
This article tracks the emergence of the concept of “transfer talk”—a concept distinct from transfer of learning—and teases out the implications of transfer talk for theories of transfer of learning.
Bodee, Bridget   +6 more
core   +1 more source

Network analysis of the worldwide footballer transfer market

open access: yes, 2018
The transfer of football players is an important part in football games. Most studies on the transfer of football players focus on the transfer system and transfer fees but not on the transfer behavior itself.
Li, Ming-Xia   +2 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Dimerization-assisted energy transport in light-harvesting complexes

open access: yes, 2010
We study the role of the dimer structure of light-harvesting complex II (LH2) in excitation transfer from the LH2 (without a reaction center (RC)) to the LH1 (surrounding the RC), or from the LH2 to another LH2.
Song, Z.   +3 more
core   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

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