Results 121 to 130 of about 4,170,262 (301)

Pavlovian-instrumental transfer effects in individuals with binge eating. [PDF]

J Eat Disord, 2023
Chan WS, Lai TT.
europepmc   +1 more source

Radiative and free-convective heat transfer from a finite horizontal plate inside an enclosure [PDF]

An experimental and analytical investigation of heat transfer from a horizontal, thin, square plate inside of an enclosure was carried out. Experimental results were obtained from both the upward-facing and the downward-facing sides of the heated plate ...
Hrycak, Peter, Sandman, D. J.
core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Transfer molding of PMR-15 polyimide resin [PDF]

, 1985
Transfer molding is an economically viable method of producing small shapes of PMR-15 polyimide. It is shown that with regard to flexural, compressive, and tribological properties transfer-molded PMR-15 polyimide is essentially equivalent to PMR-15 ...
Moyer, D. W., Nowak, B. E., Reardon, J. P.   +2 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

stGuide advances label transfer in spatial transcriptomics through attention-based supervised graph representation learning

Frontiers in Genetics
The growing availability of spatial transcriptomics data offers key resources for annotating query datasets using reference datasets. However, batch effects, unbalanced reference annotations, and tissue heterogeneity pose significant challenges to ...
Yupeng Xu, Hao Dai, Jinwang Feng, Keren Xu, Qiu Wang, Pingting Gao, Chunman Zuo, Chunman Zuo   +7 more
doaj   +1 more source

Emergence of π-Magnetism in Fused Aza-Triangulenes: Symmetry and Charge Transfer Effects. [PDF]

Nano Lett, 2023
Calupitan JP, Berdonces-Layunta A, Aguilar-Galindo F, Vilas-Varela M, Peña D, Casanova D, Corso M, de Oteyza DG, Wang T.   +8 more
europepmc   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Asymmetric negative transfer effects of working memory training. [PDF]

Mem Cognit, 2023
Ni N, Gathercole SE, Norris D, Saito S.
europepmc   +1 more source