Results 91 to 100 of about 2,532,270 (350)

Modelling and simulation techniques for forced convection heat transfer in heat sinks with rectangular fins [PDF]

open access: yes, 2009
The official published version of this article can be found at the link below.This paper provides a comprehensive description of the thermal conditions within a heat sink with rectangular fins under conditions of cooling by laminar forced convection. The
Aung   +14 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

CENTRIFUGAL COMPRESSOR EFFICIENCY CALCULATION WITH HEAT TRANSFER

open access: yesInternational Islamic University Malaysia Engineering Journal, 2017
In this paper we present a case study of apparent performance variation of an optimized centrifugal compressor design when its metal parts are cold - before the conjugated heat transfer between the fluid and parts reaches an energetic equilibrium.
Valeriu Dragan
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Heralded Storage of a Photonic Quantum Bit in a Single Atom

open access: yes, 2015
Combining techniques of cavity quantum electrodynamics, quantum measurement, and quantum feedback, we have realized the heralded transfer of a polarization qubit from a photon onto a single atom with 39% efficiency and 86% fidelity.
Kalb, Norbert   +3 more
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Fast and efficient transport of large ion clouds

open access: yes, 2015
The manipulation of trapped charged particles by electric fields is an accurate, robust and reliable technique for many applications or experiments in high-precision spectroscopy.
Champenois, Caroline   +5 more
core   +4 more sources

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

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