Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
The determinants of technology transfer efficiency and the role of innovation policies: a survey [PDF]
The diversity found in the various Technology Transfer Offices (TTOs), besides being a consequence of the capacities and motives of the different stakeholders involved (public research organisations, industry, consulting firms and public authorities ...
Aurora A.C. Teixeira +1 more
core
Energy-Efficient Power Allocation in OFDM Systems with Wireless Information and Power Transfer
, 2013 This paper considers an orthogonal frequency division multiplexing (OFDM) downlink point-to-point system with simultaneous wireless information and power transfer.
Lo, Ernest S. +2 more
core +1 more source
Dataset Artificial warming decreases heterotroph densities and trophic transfer efficiency
, 2023 Simon Bazin +15 more
openalex +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
, 2013 Elucidating quantum coherence effects and geometrical factors for efficient energy transfer in photosynthesis has the potential to uncover non-classical design principles for advanced organic materials.
Ai, Qing +3 more
core +1 more source
Rehabilitation Program After Surgical Transfer of The Ulnar Nerve to Make Anatomically Adjustment of Its route to Restore The Functional Efficiency of The Injured Hand [PDF]
, 2018 Ahmed Abdel Hamid
openalex +1 more source
Modeling Urban Transfer Stations Efficiency
Procedia Computer Science, 2016 AbstractEfficiency estimation of transit transfer stations (TTS) in densely populated urban areas is a mandatory step to define proper sustainable public transportation networks. However, due to the lack of data and the complexity of the operation patters, efficiency assessment is a cumbersome task in practice.
Román-De la Sancha, Azucena +2 more
openaire +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source