Results 121 to 130 of about 317,661 (275)

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Numerical Analysis of Magnetohydrodynamics Hybrid Nanofluid Flow Past an Infinite Vertical Plate in Presence of Thermal Radiation

Journal of Science, Innovation and Creativity
This study investigates magnetohydrodynamic (MHD) flow and heat transfer of a Cu–Al₂O₃/water hybrid nanofluid past an infinitely vertical plate, motivated by applications in energy generation, industrial cooling, and biomedical systems.
Eva Chepkirui, Maurine Wafula
doaj   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Entropy generation analysis for vertical flat and corrugated surface by natural convection and radiation at constant heat flux

Case Studies in Thermal Engineering
Previous literature has explained heat transfer by natural convection, radiation and the effect of entropy generation separately. This study focused on the entropy generation of heat transfer by natural convection and radiation instantaneously from ...
Louay Abd Al-Azez Mahdi, Hasanain A. Abdul Wahhab, Miqdam Tariq Chaichan   +2 more
doaj   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Performance enhancement mechanisms and optimization of multi-pass parallel flow condensers with liquid-vapor separation

Case Studies in Thermal Engineering
This study employed a distributed-parameter model developed by the authors to investigate the mechanisms of condensation heat transfer enhancement using liquid-vapor separation (LS) in multi-pass parallel flow condensers (MPFCs).
Jin Huan Pu, Nan Hua, Xiaodong Jian, Ying Chen, Yongliang Li, Tong Yang, Hua Sheng Wang   +6 more
doaj   +1 more source

Detection of Blood CO₂ Influences on Cerebral Hemodynamics Using Transfer Entropy. [PDF]

Entropy (Basel), 2023
Fernández-Muñoz J, Haunton VJ, Panerai RB, Jara JL.   +3 more
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Transfer Entropy on Rank Vectors

CoRR, 2010
9 pages, 7 figures, accepted in Journal of Nonlinear Systems and ...
openaire   +2 more sources