Results 281 to 290 of about 17,526,649 (388)

Biogenesis and function of tRNA fragments during sperm maturation and fertilization in mammals

Science, 2016
Upasna Sharma, C. Conine, Jeremy M. Shea, Ana Boskovic, Alan G. Derr, X. Bing, C. Belleannée, Alper Kuçukural, Ryan W Serra, F. Sun, Lina Song, Benjamin R. Carone, Emiliano P. Ricci, X. Z. Li, Lucas Fauquier, M. Moore, R. Sullivan, C. Mello, Manuel Garber, O. Rando   +19 more
semanticscholar   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

A brain functional network feature extraction method based on directed transfer function and graph theory for MI-BCI decoding tasks. [PDF]

Front Neurosci
Ma P, Dong C, Lin R, Liu H, Lei D, Chen X, Liu H.   +6 more
europepmc   +1 more source

The Lightweight Ownership Transfer Protocol using Physically Unclonable Function

, 2016
Xuejun Zhang, Wanlu Huang, He Xu, Yu Wang   +3 more
openalex   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Measurement and modeling of transfer functions for lightning coupling into the Sago mine.

, 2007
Marvin E. Morris, Matthew Higgins
openalex   +2 more sources

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Transfer function identification with filtering techniques

, 1996
Behrouz Farhang‐Boroujeny, Teng-Tiow Tay   +1 more
openalex   +2 more sources

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source