Results 161 to 170 of about 28,533,667 (307)

Assessing the Relative Performance of U.K. University Technology Transfer Offices: Parametric and Non-Parametric Evidence [PDF]

open access: yes
We present evidence on the relative efficiency of U.K. university technology transfer offices (TTOs) using data envelopment analysis (DEA) and stochastic frontier estimation (SFE). We find that U.K.
Mike Wright   +3 more
core  

Transfer Function Analysis of the Longitudinal Motion of the Common Carotid Artery Wall. [PDF]

open access: yesFront Physiol, 2016
Yli-Ollila H   +3 more
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Exploring options for the transfer of technology from the Canada-Ontario Agricultural Green Plan: Final report of the Technology Transder Committee

open access: yes, 1997
The Green Plan Technology Transfer Committee (TTC) was established to deal with concerns related to the transfer of technology and information resulting from the Canada-Ontario Green Plan.
Technology Transfer Committee of the Canada-Ontario Agricultural Green Plan
core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

CURRENT STATUS OF BENEFITS TRANSFER IN THE U.S.: A REVIEW [PDF]

open access: yes
Benefits transfer refers to the use of existing benefit estimates in a different, but similar context as compared to the original study which generated the benefit estimates.
Bergstrom, John C.
core  

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