Results 91 to 100 of about 10,380,352 (315)

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

TRANSFER LEARNING APPROACH FOR CLASSIFICATION OF WIDELY USED SPICES

open access: yesYanbu Journal of Engineering and Science, 2022
People around the world relish variety of food that are flavourful. Spices add flavours to the food without adding any fat or calories. People have used spices for many centuries and are an integral part of our food.
Arunachalam Sundaram   +3 more
doaj  

Partial Transfer Learning with Selective Adversarial Networks

open access: yes, 2017
Adversarial learning has been successfully embedded into deep networks to learn transferable features, which reduce distribution discrepancy between the source and target domains.
Cao, Zhangjie   +3 more
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Multilingual Meta-Transfer Learning for Low-Resource Speech Recognition

open access: yesIEEE Access
This paper proposes a novel meta-transfer learning method to improve automatic speech recognition (ASR) performance in low-resource languages. Nowadays, we are witnessing high interest in low-resource ASR tasks aiming at delivering feasible and reliable ...
Rui Zhou   +4 more
doaj   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Learning to Selectively Transfer [PDF]

open access: yesProceedings of the Twelfth ACM International Conference on Web Search and Data Mining, 2019
Accepted to WSDM ...
Qu, Chen   +7 more
openaire   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Structure transfer and consolidation in visual implicit learning

open access: yeseLife
Transfer learning, the re-application of previously learned higher-level regularities to novel input, is a key challenge in cognition. While previous empirical studies investigated human transfer learning in supervised or reinforcement learning for ...
Dominik Garber, József Fiser
doaj   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

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