Results 51 to 60 of about 1,977,387 (333)
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
ChildrenBackground/Objectives: Children with Developmental Coordination Disorder (DCD) frequently experience handwriting difficulties, or dysgraphia. The association between DCD and dysgraphia has long been observed and described.
Laureen Josseron +2 more
doaj +1 more source
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Science communication on TikTok: toward transformative and post-normal science
Frontiers in CommunicationScience communication on social media is becoming increasingly important in order to promote an open dialog between science and the public. This raises the question of how to present topics related to climate change in a way that is both scientific and ...
Claudia Frick +2 more
doaj +1 more source
Effective continuing education for the busy practitioner
Australasian Orthodontic Journal, 1990 This paper presents a model for maintaining a program of self-initiated study for the purposes of continuing education in orthodontics. It is suggested that the busy practitioner can gain from a clear perception of the process of learning.
Cheetham John S,
doaj +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
A faculty learning community’s reflection on implementing servicelearning goals
Journal of the Scholarship of Teaching and Learning, 2012 Implementing service-learning is challenging in light of issues such as changes in student demographics and pressure from existing curricula goals. However, closer community engagement is increasingly important in the long-term goals of our universities.
Diana Becket +2 more
doaj +2 more sources
The Role of Nonlinear Pedagogy in Supporting the Design of Modified Games in Junior Sports
Frontiers in Psychology, 2021 Nonlinear Pedagogy has been advocated as an approach that views acquisition of movement skills with a strong emphasis on exploratory behaviors and the development of individualized movement skills.
Jia Yi Chow, John Komar, Ludovic Seifert
doaj +1 more source
Combining Key-Points-Based Transfer Learning and Hybrid Prediction Strategies for Dynamic Multi-Objective Optimization [PDF]
, 2022 Yong Wang, Kuichao Li, Gai‐Ge Wang
openalex +1 more source
Grounding Language for Transfer in Deep Reinforcement Learning
, 2018 In this paper, we explore the utilization of natural language to drive transfer for reinforcement learning (RL). Despite the wide-spread application of deep RL techniques, learning generalized policy representations that work across domains remains a ...
Barzilay, Regina +2 more
core +1 more source