Results 151 to 160 of about 563,305 (257)

Transfer RNA

FEBS Letters, 2009
Ibba, Michael, Santos, Manuel A.S.
openaire   +1 more source

A transfer RNA methyltransferase with an unusual domain composition catalyzes 2'-O-methylation at position 6 in tRNA. [PDF]

Nucleic Acids Res
Matsuda T, Yamagami R, Ihara A, Suzuki T, Hirata A, Hori H.   +5 more
europepmc   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Transfer RNA and small molecule therapeutics for aminoacyl-tRNA synthetase diseases. [PDF]

FEBS J
Samuels TN, Wu F, Mahmood M, Abuzaid WA, Sun N, Moresco A, Siu VM, O'Donoghue P, Heinemann IU.   +8 more
europepmc   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Transfer RNA-derived small RNAs (tsRNAs): A rising star in liquid biopsy. [PDF]

Genes Dis
Wang Q, Pan Z, Liang S, Shi Y, Dong G, Xu L, Mao Q, Jiang F.   +7 more
europepmc   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Anticodon Engineered Transfer RNA (tRNA^SUAG) Inhibits Hepatitis B Virus Replication by Promoting the Degradation of Core Protein. [PDF]

Adv Sci (Weinh)
Yang X, Sun H, Luo Z, Zhang Q, Song Y, Li J, Liu X, Wang J.   +7 more
europepmc   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Pre-symptomatic Parkinson's disease blood test quantifying repetitive sequence motifs in transfer RNA fragments. [PDF]

Nat Aging
Madrer N, Vaknine-Treidel S, Zorbaz T, Tzur Y, Bennett ER, Drori P, Suissa N, Greenberg DS, Lerner E, Soreq E, Paldor I, Soreq H.   +11 more
europepmc   +1 more source