Results 251 to 260 of about 929,368 (351)

Neuron-Specific Glycine Metabolism Links Transfer RNA Epitranscriptomic Regulation to Complex Behaviors. [PDF]

Biol Psychiatry Glob Open Sci
Blaze J, Evans VD, Feria Pliego JA, Unichenko P, Javidfar B, Heissel S, Alwaseem H, Pennington Z, Cai D, Molina H, Henneberger C, Akbarian S.   +11 more
europepmc   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

tRF-3a-Pro: A Transfer RNA-Derived Small RNA as a Novel Biomarker for Diagnosis of Hepatitis B Virus-Related Hepatocellular Carcinoma. [PDF]

Cell Prolif
Si J, Zou Y, Gao Y, Chen J, Jiang W, Shen X, Zhu C, Yao Q.   +7 more
europepmc   +1 more source

Processing of transfer RNA precursors in a wheat mitochondrial extract.

, 1990
Pamela J. Hanic‐Joyce, Michael W. Gray
openalex   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Altered blood and keratinocyte microRNA/transfer RNA fragment profiles related to fibromyalgia syndrome and its severity. [PDF]

Pain
Erbacher C, Vaknine-Treidel S, Madrer N, Weinbender S, Evdokimov D, Unterecker S, Moshitzky G, Sommer C, Greenberg DS, Soreq H, Üçeyler N.   +10 more
europepmc   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Molecular insights into the inhibition of proton-activated chloride channel by transfer RNA. [PDF]

Cell Res
Chi P, Wang X, Li J, Yang H, Li K, Zhang Y, Lin S, Yu L, Liu S, Chen L, Ren R, Wu J, Huang Z, Geng J, Deng D.   +14 more
europepmc   +1 more source

THE TRANSFER OF MAGAZINE TRAINING BY INJECTION OF BRAIN RNA IN RATS.

, 1967
James V. McConnell, Tsuyoshi Shigehisa, Harold T. Salive   +2 more
openalex   +2 more sources

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao, Shikuan Din, Zhengkang Fu, Qian Sun, Xiwei Zhu, Yuxin Wei, Huan Qu, Xinyi Zhang, Jiaxuan Liu, Chuhua Fu, Qianxue Chen   +10 more
wiley   +1 more source