Results 271 to 280 of about 305,705 (319)

Decoding the complete mitochondrial genome of Hydrangea chinensis maxim.: insights into genomic recombination, gene transfer, and RNA editing dynamics. [PDF]

BMC Plant Biol
Ye K, Qin J, Yonghong H.
europepmc   +1 more source

Interferon‐Driven Biomarkers and Synergistic Therapy for PRMT5 Inhibition in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
Triple‐negative breast cancer exhibits variable sensitivity to PRMT5 inhibition. Basal interferon signaling is identified as a key biomarker of response. PARP inhibition with olaparib induces IFN signaling, sensitizing resistant TNBC cells to PRMT5 inhibitors.
Ziwen Zhang, Sheyu Zhang, Lu Guo, Yichun Pan, Juan Huang, Yishuai Ji, Jiaqi Tao, Yong Wei, Xiaojia Wang, Qin Wu   +9 more
wiley   +1 more source

Functions and applications of enzymes in nucleic acid nanotechnology. [PDF]

J Nanobiotechnology
Rong Q, Chu Z, Xu Y, Ma L, Wang L, Wang S, Yin Z, Su X.   +7 more
europepmc   +1 more source

Neddylation Targets and Stabilizes NLRP3 to Augment Inflammasome‐Mediated Colitis and Mood Disorder

Advanced Science, EarlyView.
NLRP3 inflammasome contributes to colitis and mood disorder. This study demonstrates that neddylation targets NLRP3 at K287, which hinders its interaction with K48‐linked ubiquitination E3 Trim31 and thereby stabilizes it. Neddylation blockade in myeloid cells and microglia mitigates DSS‐induced colitis and psychological stress‐induced anxiety‐like ...
Wenbin Gai, Mengyao Wu, Anbiao Wu, Zhaofei Jing, Zhenjie Ye, Jiayan Jin, Yaolin Zhang, Min Zhao, Genyu Liu, Xu Wang, Xiqin Yang, Jie Dong, Yunlu Xu, Jiyan Zhang   +13 more
wiley   +1 more source

An ancient influenza genome from Switzerland allows deeper insights into host adaptation during the 1918 flu pandemic in Europe. [PDF]

BMC Biol
Urban C, Vrancken B, Patrono LV, Düx A, Le Vu M, Matthes KL, Burkhard-Koren NM, Widulin N, Schnalke T, Carraro S, Rühli F, Lemey P, Staub K, Calvignac-Spencer S, Schuenemann VJ.   +14 more
europepmc   +1 more source

For "U" the bell tolls: Pseudouridine evades TLR detection. [PDF]

Mol Cell
Young AP, Kanneganti TD.
europepmc   +1 more source

Pan-mitogenome in Dipterocarpoideae: mitochondrial plastid DNAs and repeats shape the dynamic evolution of mitogenomes. [PDF]

BMC Plant Biol
Su X, Dong Z, Yu H, Yi S, Gao S, Liu J, Kan S, Zhang W.   +7 more
europepmc   +1 more source

Structural diversity and phylogenomic insights from the mitochondrial genomes of two <i>populus</i> species from the Qinghai-Tibet Plateau. [PDF]

Front Plant Sci
Huang JL, Shi YJ, Tian FF, Mi JX, Zhang F, Zhou SX, Wan XQ, Huang CD.   +7 more
europepmc   +1 more source

High-Fidelity and Cost-Effective Engineering of SARS-CoV-2. [PDF]

Viruses
Olguin-Nava M, Hennig T, Börtlein C, Bohn P, Ambi UB, Gabel A, Günter LM, Gribling-Burrer AS, Schmidt N, Caliskan N, Dölken L, Munschauer M, Smyth RP.   +12 more
europepmc   +1 more source

Complete mitochondrial genome of Persicaria maackiana reveals genome features, phylogenetic relationships, and nucleotide substitution rates. [PDF]

Sci Rep
Park KT, Kang JS, Kang D, Park SY, Choi K.   +4 more
europepmc   +1 more source