Results 61 to 70 of about 120,895 (249)
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Future InternetDuring the last decade, the cybersecurity literature has conferred a high-level role to machine learning as a powerful security paradigm to recognise malicious software in modern anti-malware systems.
Muhammad Imran +2 more
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
TGFed: Transferability-guided federated learning for unseen client adaptation
Federated learning allows multiple clients to collaboratively train a shared model by aggregating local model parameters while preserving data privacy. However, models trained via federated learning often suffer from significant performance degradation ...
Cai, J +9 more
core +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
, 2011 Ron Goeree1,2, Jing He1,2, Daria O'Reilly1,2, Jean-Eric Tarride1,2, Feng Xie1,2, Morgan Lim1,2, Natasha Burke1,21Programs for Assessment of Technology in Health (PATH) Research Institute, St Joseph's Healthcare Hamilton, ON, Canada ...
Tarride J-E +6 more
core
Object-Based Classification of Urban Areas Using VHR Imagery and Height Points Ancillary Data
Remote Sensing, 2012 Land cover classification of very high resolution (VHR) imagery over urban areas is an extremely challenging task. Impervious land covers such as buildings, roads, and parking lots are spectrally too similar to be separated using only the spectral ...
Vivek Dey +3 more
doaj +1 more source