Results 161 to 170 of about 172,724 (339)

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Transference Assessment in Psychotherapy: A Systematic Review. [PDF]

Clin Psychol Psychother
Marazzi F, Stefana A, Vecchio A, Mensi MM.   +3 more
europepmc   +1 more source

Transference and preservation of uniqueness [PDF]

, 2016
Ivan G. Todorov, Lyudmila Turowska
openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Transference and the psychological interplay in AI-enhanced mental healthcare

Frontiers in Psychiatry
Akhil P. Joseph, Akhil P. Joseph, Anithamol Babu, Anithamol Babu   +3 more
doaj   +1 more source

A quantitative figure of merit for battery SEI films and their use as functional solid-state electrolytes. [PDF]

Proc Natl Acad Sci U S A
Liu B, Zhao D, Lyle K, Yuan X, Chen PH, Zhang X, Kim JK, Wang TY, Wu H, Wang C, Yu J, Liang K, Kim JT, Liang K, Li Y.   +14 more
europepmc   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Modified cellulose-based separator with high transference number and uniform lithium deposition for dendrite-free lithium metal batteries. [PDF]

RSC Adv
Gao C, Wu L, Lu Y, Sun H, Li Y, Liu W, Luo J, Song C.   +7 more
europepmc   +1 more source

Transference of Cynanchum matsumurae T. Yamaz. to Tylophora (Asclepiadaceae)

, 2003
Tadashi Yamashiro, Yoichi Tateishi, Tetsuo Denda, Masatsugu Yokota, Masayuki Maki   +4 more
openalex   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source