Results 81 to 90 of about 165,628 (290)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Pupillary axis of a heterocentric astigmatic eye
African Vision and Eye Health, 2013 The pupillary axis of the eye is a clinically useful concept usually defined as the line through the centre of the entrance pupil that is perpendicular to the cornea.
W. F. Harris
doaj +1 more source
Forming ideal types by understanding. Application to the psychoanalytic treatment of suicidal men [PDF]
, 2010 This paper discusses the application of a qualitative methodology—forming ideal types by understanding—to the psychoanalytic psychotherapy of suicidal men. The paper focuses on a particular phase of the methodology: the validation through external expert
Briggs, Stephen, Lindner, Reinhard
core
Correlations from ion-pairing and the Nernst-Einstein equation
, 2018 We present a new approximation to ionic conductivity well suited to dynamical atomic-scale simulations, based on the Nernst-Einstein equation. In our approximation, ionic aggregates constitute the elementary charge carriers, and are considered as non ...
France-Lanord, Arthur +1 more
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Forum: Qualitative Social Research, 2003 The theoretical discussion reflects the correspondence and methodological synergy between the narration theory in qualitative social research studies and the concepts of narration applied in object-relation psychoanalysis and psychotraumatology.
Harald Weilnböck
doaj
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
When the Unconscious Joins the Game: A Psychoanalytic Perspective on Modernization and Change
Forum: Qualitative Social Research, 2003 The article presents a psychoanalytic and cultural perspective on the modernization of the welfare state in a Danish context. The article analyzes the processes of change and development in public welfare organizations through theoretical and empirical ...
Linda Lundgaard Andersen
doaj