Results 1 to 10 of about 335,076 (311)
Del límite de la urbanización al límite de lo urbano: la construcción territorial del gran París y el gran Madrid (1910-1939) [PDF]
Town planning practice and discourses experienced a parallel evolution in Madrid and Paris during the first decades of 20th Century. International models and tools were adapted to the local context and to the new challenges of the greater city.
Beatriz Fernández Águeda
doaj
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
The aim of this work is to simulate experimentally a plume of fire placed at different heights evolving inside a horizontal tunnel, in order to determine the effect of the source site on the plume structure.
Hatem SAAFI +2 more
doaj +1 more source
Statistical relationships among the variables of a complex system reveal a lot about its physical behavior[...]
openaire +6 more sources
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
The article is devoted to the study of mechanisms to organize relations inside the budget system of Ukraine and Europe effectively, namely through developing theoptimal balance between the central government budget and the budgets of local governments ...
O. Iafinovych
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Fiscal Equalization in the System of Financial Support of Ukraine’s Regions: the Current State and Vector of Development [PDF]
The peculiarities in the functioning of the current system of inter-budget relations in Ukraine from the perspective of its impact on the regional development have been disclosed.
Voznyak Halyna V.
doaj

