Nerve transfers for the upper extremity function restoration. [PDF]
Brain SpineRasulić L, Savić A, Lepić M.
europepmc +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Cross-Border Information Transfers: Evidence from Profit Warnings Issued by European Firms [PDF]
This paper reports evidence on cross-border accounting information transfers associated with profit warning announcements. Using a sample of firms from 29 European countries, we find that negative earnings surprises disclosed by firms in one country ...
Paulo Alves, Peter Pope, Steven Young
core
Immediate Nerve and Tendon Transfers After Wide Resection of a Radial Nerve Malignant Peripheral Nerve Sheath Tumor: A Case Report and Surgical Technique. [PDF]
Perm JZhou J +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Income Distribution and Public Transfers as Social Safety Nets in Korea [PDF]
Using 5-year balanced household panel data, this paper shows that the inequality of per capita income in Korea aggravated during the financial crisis in 1998.
Man Woo Lee, Sung Jin Kang
core
Operative Management and Time to Procedure for Transferred versus Direct-arrival Supracondylar Humerus Fractures at a Non-trauma-designated Children's Hospital. [PDF]
J Pediatr Soc North AmNelson DR +4 more
europepmc +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
The reconstructive burden of inter-hospital transfers: resource utilization and clinical implications in tertiary trauma care. [PDF]
Front SurgKim MJ, Cho HG, Lee IJ, Lim H.
europepmc +1 more source