Results 111 to 120 of about 235,831 (265)

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

Sustainable bioplastics manufacturing from renewable sources

open access: yesFEBS Open Bio, EarlyView.
Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto   +6 more
wiley   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

open access: yesFEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen   +6 more
wiley   +1 more source

Application of the inverse Laplace transform techniques to solve the generalized Bagley–Torvik equation including Caputo’s fractional derivative

open access: yesPartial Differential Equations in Applied Mathematics
This article employs the Laplace transform approach to solve the Bagley–Torvik equation including Caputo’s fractional derivative. Laplace transform is a powerful method for enabling solving integer and non-integer order ODEs and PDEs in engineering and ...
Dania Santina   +4 more
doaj   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

A New Method for Complex Impedance Measurement of Power Transformers via a Continuous Wavelet Transform

open access: yesEnergies
The Fourier transform is widely accepted as the time-to-frequency conversion procedure, although it has some limitations. Currently, measurements in the time domain are usually transient (non-periodic waveforms) within a finite window time and discrete ...
Eduardo Gómez-Luna   +2 more
doaj   +1 more source

Intermediate Domain System Identification Using Walsh Transforms

open access: yesIFAC Proceedings Volumes, 1982
Abstract A system identification method is proposed which utilises both the ability of the time-invariant linear (TIL) system to model actual phenomena, and the computational advantages associated with the dyadic-invariant linear (DIL) system, which is based on the complete orthonormal set of Walsh functions.
openaire   +2 more sources

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

open access: yesFEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

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