Results 81 to 90 of about 235,831 (265)

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Secure and Robust Image Watermarking Scheme Using Homomorphic Transform, SVD and Arnold Transform in RDWT Domain

open access: yesAdvances in Electrical and Electronic Engineering, 2019
The main objective for a watermarking technique is to attain imperceptibility, robustness and security against various malicious attacks applied by illicit users. To fulfil these basic requirements for a scheme is a big issue of concern.
Priyank Khare, Vinay Kumar Srivastava
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

CGFTNet: Content-Guided Frequency Domain Transform Network for Face Super-Resolution

open access: yesInformation
Recent advancements in face super resolution (FSR) have been propelled by deep learning techniques using convolutional neural networks (CNN). However, existing methods still struggle with effectively capturing global facial structure information, leading
Yeerlan Yekeben, Shuli Cheng, Anyu Du
doaj   +1 more source

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