Results 111 to 120 of about 231,375 (285)

ViTAE-SL: A vision transformer-based autoencoder and spatial interpolation learner for field reconstruction

Computer Physics Communications
Reliable and accurate reconstruction for large-scale and complex physical fields in real-time from limited observations has been a longstanding challenge. In recent years, sensors have been increasingly deployed in numerous physical systems. However, the locations of these sensors can shift over time, such as with mobile sensors, or when sensors are ...
Fan, Hongwei, Cheng, Sibo, de Nazelle, Audrey, Arcucci, Rossella   +3 more
openaire   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Rapid parameter estimation for merging massive black hole binaries using continuous normalizing flows

Machine Learning: Science and Technology
Detecting the coalescences of massive black hole binaries (MBHBs) is one of the primary targets for space-based gravitational wave observatories such as laser interferometer space antenna, Taiji, and Tianqin. The fast and accurate parameter estimation of
Bo Liang, Minghui Du, He Wang, Yuxiang Xu, Chang Liu, Xiaotong Wei, Peng Xu, Li-e Qiang, Ziren Luo   +8 more
doaj   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Construction and Application of a Real-time Grid Interpolation Station Service Based on Platform Tianqing

应用气象学报
In response to the disruption of observation collection or transformation by extreme disastrous weather and subsequent destruction of automatic weather stations and communication facility, upstream and downstream relationships of grid real-time analysis ...
He Lin, Zhang Yabin, Xiao Weiqing, Huo Qing, Ji Qing, Feng Jieqiong   +5 more
doaj   +1 more source

T-GMSI: A transformer-based generative model for spatial interpolation under sparse measurements

Generating continuous environmental models from sparsely sampled data is a critical challenge in spatial modeling, particularly for topography. Traditional spatial interpolation methods often struggle with handling sparse measurements. To address this, we propose a Transformer-based Generative Model for Spatial Interpolation (T-GMSI) using a vision ...
Tian, Xiangxi, Shan, Jie
openaire   +2 more sources

Interdisciplinary Fairness in Imbalanced Research Proposal Topic Inference: A Hierarchical Transformer-based Method with Selective Interpolation

ACM Transactions on Knowledge Discovery from Data
The objective of topic inference in research proposals aims to obtain the most suitable disciplinary division from the discipline system defined by a funding agency. The agency will subsequently find appropriate peer-review experts from their database based on this division.
Meng Xiao, Min Wu, Ziyue Qiao, Yanjie Fu, Zhiyuan Ning, Yi Du, Yuanchun Zhou   +6 more
openaire   +2 more sources

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source