Results 61 to 70 of about 231,375 (285)

TRAJECTORY PLANNING AND SIMULATION STUDY OF B-AXIS POWER TOOL HOLDER

Jixie qiangdu, 2020
To study the pose state and coordinate transformation of different tool positions by establishing the interpolation equations,and obtain the mathematical model between the coordinate systems,and verify the validity according to the simulation results ...
LI XinWen, LI YuLian
doaj  

Unified Approach to Crossover Phenomena

, 1998
A general analytical method is developed for describing crossover phenomena of arbitrary nature. The method is based on the algebraic self-similar renormalization of asymptotic series, with control functions defined by crossover conditions.
Gluzman, S., Yukalov, V. I.
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Scale Analysis on Unstructured Grids: Kinetic Energy and Dissipation Power Spectra on Triangular Meshes

Journal of Advances in Modeling Earth Systems, 2023
Fourier spectra are powerful tools to analyze the scale behavior of turbulent flows. While such spectra are mathematically based on regular periodic data, some state‐of‐the‐art ocean and climate models use unstructured triangular meshes.
S. Juricke, K. Bellinghausen, S. Danilov, A. Kutsenko, M. Oliver   +4 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

A new relativistic hydrodynamics code for high-energy heavy-ion collisions

, 2016
We construct a new Godunov type relativistic hydrodynamics code in Milne coordinates, using a Riemann solver based on the two-shock approximation which is stable under the existence of large shock waves.
Akamatsu, Yukinao, Nonaka, Chiho, Okamoto, Kazuhisa   +2 more
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Generalized Cardinal Polishing Splines Signal Reconstruction

Mathematics
Sampling and reconstruction are indispensable processes in signal processing, and appropriate foundations are crucial for spline reconstruction models.
Fangli Sun, Zhanchuan Cai
doaj   +1 more source