Results 41 to 50 of about 2,980,329 (253)

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

Students’ Mathematical Reasoning in Learning of Transformation Geometry [PDF]

open access: yes, 2020
Mathematical reasoning is component that must be built by students.  Mathematical reasoning plays an important role in solving problems and delivering ideas in learning mathematics.
Qohar, Abd, Adiafidah, Rosa Amalia
core   +1 more source

Transformation geometry. Leonardo da Vinci's urban proposal for Milan

open access: yesEGA, 2016
In 1493, Leonardo da Vinci proposed an ambitious plan for the transformation of Milan, consisting of the construction of ten new cities in order to solve overcrowding and insalubrity problems at the Lombard capital.
Enrique Fernandez-Vivancos González
doaj   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

open access: yesMolecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Linear algebra, geometry and transformation

open access: yes, 2014
Vectors, Mappings and Linearity Numeric Vectors Functions Mappings and Transformations Linearity The Matrix of a Linear Transformation Solving Linear Systems The Linear SystemThe Augmented Matrix and RRE Form Homogeneous Systems in RRE Form Inhomogeneous
Solomon, Bruce, Bruce Solomon
core   +1 more source

EXPLORATION GEOMETRY TRANSFORMATION CONCEPT FROM SAMARINDA SARONG [PDF]

open access: yes, 2021
Samarinda sarong is a masterpiece or special craft that lived in Samarinda city and one of the most icon from this city. This culture should be able to give attention to the people of Samarinda, because through education based on local wisdom it is able ...
Sugeng, Sugeng   +5 more
core   +1 more source

Exploration of Relational Thinking Skills Using Problem Solving of Geometry Transformation

open access: yesKreano: Jurnal Matematika Kreatif-Inovatif, 2021
The aimed study is analyzing the mathematical ability of students with relational thinking skills in geometry transformation material. This study used a descriptive qualitative approach.
Sahrul Ramadhan   +2 more
doaj   +1 more source

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

open access: yesMolecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna   +8 more
wiley   +1 more source

Pengaruh Readiness dan Self-Confidence terhadap Penguasaan Geometri Transformasi Mahasiswa Pendidikan Matematika Universitas Muhammadiyah Purworejo

open access: yesBeta: Jurnal Tadris Matematika, 2016
[Bahasa]: Penelitian kuantitatif ini bertujuan untuk mengetahui adanya pengaruh positif dan signifikan antara readiness, self-confidence, serta readiness dan self-confidence secara bersama-sama terhadap penguasaan  mahasiswa pada mata kuliah Geometri ...
Erni Puji Astuti   +2 more
doaj   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

open access: yesMolecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi   +2 more
wiley   +1 more source

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