Parkinson Disease Subtype Stability and Eventual Convergence
ABSTRACT Objective Previous research identified distinct Parkinson disease (PD) clinical subtypes of “Motor Only,” “Psychiatric & Motor,” and “Cognitive & Motor” based on comprehensive, multidomain classification. Whether these subtypes reflect distinct trajectories or progressive disease stages remains unknown.
Laura M. Rosok +10 more
wiley +1 more source
A New Ordered Transformation-Induced Plasticity Enables Exceptional Strength and Ductility in a B2 Medium-Entropy Alloy. [PDF]
Li C +8 more
europepmc +1 more source
ABSTRACT Objective Febrile seizures (FS) are currently classified as simple or complex primarily to describe seizure characteristics, with limited ability to identify the underlying etiology. We evaluated whether molecular diagnosis could complement conventional classification and improve the diagnosis and management of FS.
Jia Wang +22 more
wiley +1 more source
Analog Tensor Processing With Carbon Nanotube In-Memory Matrix Multiplications for Edge Computer Vision Acceleration. [PDF]
Pei J +11 more
europepmc +1 more source
Four‐Year Cognitive Outcomes in Multiple Sclerosis: Associations With Lesion Myelin Integrity
ABSTRACT Objectives Cognitive impairment is prevalent in patients with multiple sclerosis (MS) but whether lesion myelin integrity influences future cognitive outcomes remains unclear. We investigated the relationship between baseline lesion myelin water fraction (MWF) and cognitive performance 4 years later.
Iliana Pliska‐Bloch +9 more
wiley +1 more source
From Molecular Alterations to Risk Prediction: Biomarkers of Actinic Keratosis Progression to Cutaneous Squamous Cell Carcinoma. [PDF]
Meyer T +5 more
europepmc +1 more source
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos +2 more
wiley +1 more source
Evaluation of the high-quality development of graduate education in mining engineering based on ISM and Bayesian networks. [PDF]
Wu L, Sun Z, Yang Y.
europepmc +1 more source
Objective Orofacial manifestations are significantly impactful in patients with systemic sclerosis (SSc) yet remain understudied, with no dedicated clinical guidelines to inform their management. Methods An international online survey comprised38 questions addressing orofacial manifestations of SSc, including patients’ confidence in their treating ...
Eleni Deligianni +4 more
wiley +1 more source
Patients improve, patterns persist: longitudinal stability of RA joint involvement patterns
Objective Rheumatoid arthritis is a heterogeneous disease. Data‐driven approaches, from synovial histology to joint involvement patterns (JIPs), have sought to define clinically meaningful subgroups. Whether these subgroups represent stable phenotypes or transient disease states remains unclear.
Tjardo Maarseveen +24 more
wiley +1 more source

