Residue Dissipation, Transformation Products, and Dietary Risk Assessment of Flonicamid in a Rice Paddy Ecosystem. [PDF]
Fu Y, Wang Q, Zhang L, Wu Y.
europepmc +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Persistence and mobility of metazachlor and its metabolites in soils: Why transformation products pose a greater groundwater risk. [PDF]
Kodešová R +7 more
europepmc +1 more source
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Remediation of organic pollutants by Fenton-like reactions with spinel catalysts: pathways, transformation products, and reactor perspectives. [PDF]
Husak V +3 more
europepmc +1 more source
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
Environmental Fate of Emerging Contaminants and Their Transformation Products in Mexican Aquatic Systems: Distribution, Persistence, Monitoring Gaps, and Removal. [PDF]
Pérez Bravo SG +5 more
europepmc +1 more source
ShinyTPs: Curating Transformation Products from Text Mining Results. [PDF]
Palm EH +6 more
europepmc +1 more source
CEACAM1 participation in breast cancer progression
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source

