Results 41 to 50 of about 462,568 (264)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Effect of Different Proteases on the Enzymatic Hydrolysis Efficiency and Structure of Wheat Gluten
Shipin gongye ke-jiThis study aimed to investigate the enzymatic hydrolysis effects of papain, alkaline protease, neutral protease, alkaline protease TG enzyme combination, and papain alkaline protease combination on gluten protein and their impact on its structure.
Xiangjun LIU +5 more
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Intelligent Productivity Transformation
Journal of Organizational and End User ComputingWith the penetration of deep learning technology into forecasting and decision support systems, enterprises have an increasingly urgent need for accurate forecasting of time series data. Especially in fields such as finance, retail, and production, immediate and accurate predictions of market trends are the key to maintaining a competitive advantage ...
Bojing Liu +4 more
openaire +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Soy protein isolate-chitosan complex condensate: Phase behavior, structure and functional properties
Food Chemistry: XThis study investigated the interaction mechanism between soy protein isolate (SPI) and chitosan (CS), and the structure and functional properties of their complex.
Xiongzhi Li +5 more
doaj +1 more source
Molecules, 2019 The knowledge of transformation pathways and identification of transformation products (TPs) of veterinary drugs is important for animal health, food, and environmental matters.
Lisa Kotthoff +3 more
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Protective Effect of Peach Gum Polysaccharides on DSS-induced Ulcerative Colitis in Mice
Shipin gongye ke-jiObjective: To investigate the protective effect of peach gum polysaccharides (PGP) on ulcerative colitis induced by dextran sulfate sodium (DSS) in mice.
Rui DING +6 more
doaj +1 more source