Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Capacity building through integration and transformational leadership - A case study
Higher Learning Research Communications, 2011 This article suggests that educational managers can have an influence through leadership by establishing certain moderators that integrate and shape the faculty into a solid team working towards a high performing organisation.
Sacha Michael Stocklin
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
The Relationship Between Transformational Leadership, Empowerment and Organizational Commitment: a Mediating Model Testing [PDF]
The human resource development literature highlights that properly implemented transformational leadership style may have a significant impact on the organizational commitment.
Azman ISMAIL, Munirah Hanim YUSUF
core
Improving School Leadership: The Connection of Transformational Leadership and Psychological Well-Being of the Followers [PDF]
, 2018 In this current era of public school accountability in the United States, the passage of No Child Left Behind resulted in dramatic changes for public school districts (U.S. Department of Education, 2001).
Bryant, Pamela +2 more
core +1 more source
Galilean Transformation, Lorentz Transformation, and General Transformation
, 2022 Abstract In the Galilean transformation system, a body contacts and moves on the moving frame and is completely carried by the moving frame and hence the body and the moving frame have the same time rule but velocity of the body moving in the stationary frame is larger than in the moving frame.
openaire +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Leadership styles and organisational communication in selected public universities in Uganda
Interdisciplinary Journal of Management SciencesThis study aimed to assess the impact of leadership styles on organisational communication in selected public universities in Uganda. Specifically, the study examined the influence of transformational and transactional leadership styles on organisational
Wilberforce Turyahikayo +2 more
doaj +1 more source
Empiricism without Magic: Transformational Abstraction in Deep Convolutional Neural Networks [PDF]
, 2018 In artificial intelligence, recent research has demonstrated the remarkable potential of Deep Convolutional Neural Networks (DCNNs), which seem to exceed state-of-the-art performance in new domains weekly, especially on the sorts of very difficult ...
Buckner, Cameron
core +1 more source
Acceptability with general orderings
, 2001 We present a new approach to termination analysis of logic programs. The essence of the approach is that we make use of general orderings (instead of level mappings), like it is done in transformational approaches to logic program termination analysis ...
A. Bossi +18 more
core +2 more sources