Results 131 to 140 of about 434,849 (334)

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Mathematical modeling and experimental research on grounding current calculation of converter transformer core

open access: yesMeasurement + Control
When the converter transformer core is grounded at multi-points, a fault loop will be formed and a circulation will be generated, leading to local overheating of the magnetic core and decomposition of insulating oil.
Xiu Zhou   +6 more
doaj   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Multiple objectives escaping bird search optimization and its application in stock market prediction based on transformer model

open access: yesScientific Reports
Stock market prediction has long attracted the attention of academia and industry due to its potential for substantial financial returns. Despite the availability of various forecasting methods, such as CNN, LSTM, BiLSTM, GRU, and Transformer, the ...
Dedai Wei   +7 more
doaj   +1 more source

Time, the final frontier

open access: yesMolecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain   +3 more
wiley   +1 more source

Transforming the transformed [PDF]

open access: yesInternational Journal of Heritage Architecture: Studies, Repairs and Maintence, 2017
openaire   +2 more sources

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