Results 81 to 90 of about 14,646 (305)

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Time domain analysis of switching transient fields in high voltage substations [PDF]

, 2009
Switching operations of circuit breakers and disconnect switches generate transient currents propagating along the substation busbars. At the moment of switching, the busbars temporarily acts as antennae radiating transient electromagnetic fields within ...
Judd, M.D., Musa, B.U., Siew, W.H.
core  

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Comparison of different classification algorithms for fault detection and fault isolation in complex systems [PDF]

, 2018
Due to the lack of sufficient results seen in literature, feature extraction and classification methods of hydraulic systems appears to be somewhat challenging.
Jung, Marcel, Niculita, Octavian, Skaf, Zakwan   +2 more
core   +2 more sources

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

RETRACTED: Fault Diagnosis of Traction Transformer Based on Bayesian Network

Energies, 2020
As the core equipment of a traction power supply system, the traction transformer is very important to ensure the safe and reliable operation of the system. At present, the three-ratio method is mainly used to distinguish transformer faults, whereas such
Yong Xiao, Weiguo Pan, Xiaomin Guo, Sheng Bi, Ding Feng, Sheng Lin   +5 more
doaj   +1 more source

A transformer fault diagnosis method based on hybrid improved grey wolf optimization and least squares‐support vector machine

IET Generation, Transmission & Distribution, 2022
In recent years, support vector machine has been widely used in the field of transformer fault diagnosis, but its fault diagnosis performance is still to be improved.
Yuhan Wu, Xianbo Sun, Baofu Dai, Pengfei Yang, Zhihao Wang   +4 more
doaj   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

TSViT: A Time Series Vision Transformer for Fault Diagnosis of Rotating Machinery

Applied Sciences
Efficient and accurate fault diagnosis of rotating machinery is extremely important. Fault diagnosis methods using vibration signals based on convolutional neural networks (CNNs) have become increasingly mature.
Shouhua Zhang, Jiehan Zhou, Xue Ma, Susanna Pirttikangas, Chunsheng Yang   +4 more
doaj   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source