Results 191 to 200 of about 85,416 (307)

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Implementing generative pretrained transformer models for text recognition tasks in safety data sheets. [PDF]

Ann Work Expo Health
Pekel F, Kalkman G, Lemcke E, van Stokkum R, Pronk A, Godderis L, Goossens J, De Raeve H, Coene E, Kuijpers E.   +9 more
europepmc   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Classifying human vs. AI text with machine learning and explainable transformer models. [PDF]

Sci Rep
Masih A, Afzal B, Firdoos S, Mahmood J, Ali A, Abdulnabi MS, Balungu DM.   +6 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Chat Demeter: a multi-agent system for plant disease diagnosis integrating CNN-transformer models. [PDF]

Front Plant Sci
Zhang S.
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Enhancing cyberbullying detection with RoBERTa: A transformer-based approach

This study investigates the effectiveness of transformer-based models, specifically RoBERTa, in detecting cyberbullying on social media platforms compared to traditional machine learning models such as Random Forest (RF) and Long Short-Term Memory (LSTM).
Azhar, H., Runa, A.
core  

Leveraging Transformer Models for Genre Classification

As the digital music landscape continues to expand, the need for effective methods to understand and contextualize the diverse genres of lyrical content becomes increasingly critical.
Hughes, Yves, Horn, Hayley, Berger, Ben, Craus, Andreea C   +3 more
core   +1 more source

GAN-Based Cross-Modality Brain MRI Synthesis: Paired Versus Unpaired Training and Comparison with Diffusion and Transformer Models. [PDF]

Biomimetics (Basel)
Kiani Kalejahi B, Danishvar S, Rajabi MJ.   +2 more
europepmc   +1 more source