Results 91 to 100 of about 31,975 (291)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Measurement of Short-Circuit Effects on Transformer Winding with SFRA Method and Impact Test

Metrology and Measurement Systems, 2016
The paper presents theoretical and experimental analyses of a possible effect of the short-circuit forces on the transformer winding. The first part of the paper is focused on creation and activity of the radial and axial forces during a short circuit ...
Gutten Miroslav, Janura Richard, Šebök Milan, Korenčiak Daniel, Kučera Matej   +4 more
doaj   +1 more source

Research and Application of Contactless Measurement of Transformer Winding Tilt Angle Based on Machine Vision. [PDF]

Sensors (Basel), 2023
Xu J, Zheng S, Sun K, Song P.
europepmc   +1 more source

High voltage pulse generator Patent [PDF]

, 1970
High voltage pulse generator for testing flash and ignition limits of nonmetallic materials in controlled ...
Pippen, D. L.
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Analysis of Leakage Impedance Variations Due to Cross-Sectional Area Changes in High Voltage Sections

IEEE Access
Transformers are crucial devices in electrical power systems, playing a key role in voltage regulation, power transmission, and distribution. Leakage impedance is one of the main factors influencing the transformer’s performance. Leakage impedance
Kamran Dawood, Semih Tursun, Guven Komurgoz   +2 more
doaj   +1 more source

Pembangunan dan penilaian sistem 'template' soal selidik berasaskan web (e-templete questionnaire) [PDF]

, 2003
Kajian ini dijaiankan bagi meninjau keboiehgunaan dan tahap mesra pengguna terhadap g-?e?77p/a/g soal selidik. Fokus utama kajian ini adaiah (i) menilai tahap keboiehgunaan
Abu Bakar, Muhammad Helmi
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Sustained arc ignition system [PDF]

, 1977
Circuitry for maintaining an arc or spark across a spark gap for a desired length of time is disclosed. A high voltage, direct current source is connected in series with a secondary winding of a high voltage, stepup transformer or coil and a spark gap ...
Birchenough, A. G.
core   +1 more source