Results 61 to 70 of about 31,975 (291)
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Real Time Measurement of Average Winding Resistances of Transformers
Gazi Üniversitesi Fen Bilimleri Dergisi, 2018 The monitoring of transformers that are expensive equipment of power systems is the one of important issues. Transformer monitoring systems are usually used in order to detect failures, to determine the lifetime, to measure losses and to monitor winding
Cenk GEZEGİN +2 more
doaj +1 more source
Electronically resettable fuse Patent [PDF]
, 1971 Development and characteristics of electronically resettable fuse with saturable core current sensing transformer having two outside legs and center ...
Genter, R. E.
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Methodology to locate and quantify radial winding deformation in power transformers
High Voltage, 2017 Frequency response analysis (FRA) is a tool that can be used to detect changes within the structural geometry of a transformer. One application of FRA is to detect winding displacement after the transformer experiences an overcurrent event.
Steven D. Mitchell, James S. Welsh
doaj +1 more source
A novel energy router based on multi‐winding line frequency transformer
IET Generation, Transmission & Distribution, 2023 Energy routers based on the electronic power transformer are suitable for the AC–DC hybrid grid with multiple voltage levels, but their structures are complex.
Zhitao Guan +4 more
doaj +1 more source
Increasing efficiency of switching type regulator circuits Patent [PDF]
, 1968 Switching series regulator with gating control ...
Clapp, W. M.
core +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
AIP AdvancesWith the increasing demand for the resilient capacity of transformers in high-proportion renewable energy grids, the overload capacity of transformers and the thermal conductivity of winding insulation materials have been put forward as important ...
Haomin Li +4 more
doaj +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source