Results 91 to 100 of about 122,577 (296)

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Efficient Scaling of Bayesian Neural Networks

open access: yesIEEE Access
While Bayesian neural networks (BNNs) have gained popularity for their theoretical guarantees and robustness, they have yet to see a convincing implementation at scale.
Jacob R. Epifano   +3 more
doaj   +1 more source

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

open access: yesFEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual   +3 more
wiley   +1 more source

A Novel Open-Domain Question Answering System on Curated and Extracted Knowledge Bases With Consideration of Confidence Scores in Existing Triples

open access: yesIEEE Access
In this paper, we present a novel approach to improving Open-Domain Knowledge Base Question Answering by leveraging both curated (Freebase) and extracted (Reverb) knowledge bases. Our hybrid system combines Span Detection using BERT (SD-BERT) for precise
Somayyeh Behmanesh   +3 more
doaj   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

open access: yesFEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng   +8 more
wiley   +1 more source

Types and Construction of Power Transformers

open access: yes, 2017
Transformers may be classified according to dielectric insulation material as follows: • Oil-filled transformers• Dry type ...
Manuel Bolotinha
core   +1 more source

Automatic Translation between Mixtec to Spanish Languages Using Neural Networks

open access: yesApplied Sciences
This paper introduces a novel method for collecting and translating texts from the Mixtec to the Spanish language. The method comprises four primary steps.
Hermilo Santiago-Benito    +5 more
doaj   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

open access: yesFEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan   +4 more
wiley   +1 more source

Fake News Classification Methodology With Enhanced BERT

open access: yesIEEE Access
News serves as a vital source of information for staying updated on various aspects of life worldwide. However, massive volume of information available on social media platforms makes it challenging to extract meaningful insights.
Ammar Oad   +5 more
doaj   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

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