Results 91 to 100 of about 116,350 (298)

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Bridging in contaminated transformer oil under DC and AC electric field

open access: yes, 2013
One of the key components in high voltage transmission and distribution systems are power transformers and their consistent operation is of utmost importance to energy utilities and users.
Wilson, G   +9 more
core   +1 more source

Numerical Homogenization for the Calculation of Eddy Current Losses in a Laminated Open Core

open access: yesIEEE Access
Eddy currents are decoupled into narrow eddy currents, induced by the magnetic flux tangential to the laminations, and planar eddy currents, induced by the magnetic flux perpendicular to the laminations.
Stjepan Frljic   +2 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Efficient Scaling of Bayesian Neural Networks

open access: yesIEEE Access
While Bayesian neural networks (BNNs) have gained popularity for their theoretical guarantees and robustness, they have yet to see a convincing implementation at scale.
Jacob R. Epifano   +3 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Energy Saving Application of Distribution Transformers in Urban Rail Transit

open access: yesChengshi guidao jiaotong yanjiu
ObjectiveTo analyze the operational characteristics of capacity reduction for urban rail transit distribution transformers from the perspectives of economy and reliability, a comprehensive applicability analysis of amorphous alloy distribution ...
Mingyang CI   +5 more
doaj   +1 more source

A Novel Open-Domain Question Answering System on Curated and Extracted Knowledge Bases With Consideration of Confidence Scores in Existing Triples

open access: yesIEEE Access
In this paper, we present a novel approach to improving Open-Domain Knowledge Base Question Answering by leveraging both curated (Freebase) and extracted (Reverb) knowledge bases. Our hybrid system combines Span Detection using BERT (SD-BERT) for precise
Somayyeh Behmanesh   +3 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Automatic Translation between Mixtec to Spanish Languages Using Neural Networks

open access: yesApplied Sciences
This paper introduces a novel method for collecting and translating texts from the Mixtec to the Spanish language. The method comprises four primary steps.
Hermilo Santiago-Benito    +5 more
doaj   +1 more source

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