Results 141 to 150 of about 122,577 (296)
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Electric transformers and PCBs
, 2000 Title from Web page (viewed Jan. 22, 2008).; "November 29, 2000."; Discusses what proportion of Connecticut Light & Power (CL&P) transformers are contaminated with polychlorinated biphenyls (PCBs), whether the company has a program to replace these ...
McCarthy, Kevin E. (Kevin Edward), 1954-
core
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Correction: Detecting reconciliation discrepancies in tabular data using transformers. [PDF]
Front Artif IntellDu Plessis C, Wa Nkongolo M.
europepmc +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Transformers for fMRI analysis: from spatiotemporal modeling to brain foundation models. [PDF]
Front NeuroinformYang X, Li Y, Zhang X, Wang B.
europepmc +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Low power current transformers
, 2018 Master‘s thesis is focused on current instrument transformers, current sensors and low power current transformers. Discussion is made on advantages and disadvantages of each measuring principle.
Zolich, Ladislav
core
Generative Artificial Intelligence Models in Breast Cancer Diagnosis: A Systematic Review. [PDF]
Diagnostics (Basel)Musa ZM, Kakudi HA.
europepmc +1 more source