Results 231 to 240 of about 122,577 (296)

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

SLIC-Former: a superpixel-guided transformer framework for automatic liver segmentation in CT images. [PDF]

Sci Rep
Elqersh SF, Haikal AY, Saafan MM, Sakr NA.   +3 more
europepmc   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

A Lightweight Conformer-Based Framework for Medical Image Classification. [PDF]

J Imaging
Vijayasree S, Krishna A, Nair AS, Alex A, Jayakrishnan SK, Nair JJ.   +5 more
europepmc   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

From Pixel Modification to Generative Synthesis: A Survey of Deep Learning for Image Data Hiding. [PDF]

J Imaging
Janok M, Forgáč R, Hluchý L.
europepmc   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

The Use of Deep Learning in RNA Therapeutic Development. [PDF]

ACS Nano
Subramanian DA, Yao SL, Chan A, Witten J, Reker D, Anderson DG, Langer R, Traverso G.   +7 more
europepmc   +1 more source

Malignant transformation of lower-grade glioma: contrast enhancement, extent of resection, and the natural history under interval-censored analysis. [PDF]

J Neurooncol
Atli B, Wartha M, Gmeiner M, Aichholzer M, Weis S, Vorhauer D, Wagner H, Hauer T, Serra C, Böhm P, Sonnberger M, Stroh-Holly N, Aspalter S, Aufschnaiter K, Rossmann T, Gollwitzer M, Ziai J, Leibetseder A, Pichler J, Thomae W, Dorfer C, Gruber A, Stefanits H, Rauch P.   +23 more
europepmc   +1 more source

Fine-grained avian wildlife species classification: a comparative study of MambaVision, vision transformers, and CNN architectures. [PDF]

BMC Ecol Evol
Kulsrrestha R, Pal C, Jain R, Jaiswal R, Kaur A.   +4 more
europepmc   +1 more source