Results 61 to 70 of about 122,577 (296)
To transform or not to transform [PDF]
Plant Signaling & Behavior, 2011 Chemical ecology, be it the study of plant volatiles or insect cuticular hydrocarbons, largely involves the analysis of compositions or "blends" of a mixture of compounds. Compositional data have intrinsic properties such as a "constant-sum constraint" which should be taken into account when statistically analysing these data.
Yuvaraj, Ranganathan, Renee M, Borges
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
EnergiesHigh voltage connections will discharge through inductive voltage and combined transformers when they are switched off. In the past, there was a wide margin between the required capabilities and the actual capabilities of these components.
Andrea Grđan +5 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Power Electronics and DrivesIn the design process of a photovoltaic (PV) power plant, determination of the maximum power that can be extracted from the PV modules is essential, especially for the dimensioning of the individual parts of the plant.
Najdoska Angela, Cvetkovski Goga
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Transformations Debugging Transformations.
, 2017 Abstract: Practical model transformation (MT) frameworks are usually composed of multiple execution contexts, building an overall workflow by abstracting different aspects of execution. This heterogeneity brings additional challenges to debugging, which must address a combination of quite different graphical and textual formalisms.
Jukks, Maris +2 more
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Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
IET Electric Power ApplicationsPermanent magnet synchronous motors (PMSMs) experience considerable performance degradation due to the rise in temperature and the resulting partial demagnetisation in the PMs, as well as the shortenings in the insulations' lifetime.
Tohid Sharifi
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Genome biology, 2006 The Nobel process for science are often somewhat controversial for who they omit. A posthumous Nobel honor could help recognize some neglected heroes.
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Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source