Results 131 to 140 of about 9,530,351 (265)

Resveratrol inhibits transforming growth factor-β2-induced epithelial-to-mesenchymal transition in human retinal pigment epithelial cells by suppressing the Smad pathway

, 2017
Ching-Long Chen,1,2 Yi-Hao Chen,1,2 Ming-Cheng Tai,2 Chang-Min Liang,2 Da-Wen Lu,1,2 Jiann-Torng Chen1,2 1Graduate Institute of Medical Science, National Defense Medical Center, Taipei, Taiwan; 2Department of Ophthalmology, Tri-Service General Hospital,
Chen CL, Tai MC, Liang CM, Chen JT, Chen YH, Lu DW   +5 more
core  

Transforming growth factor beta-1 level in pleural effusion

, 2003
Objective: Transforming growth factor-beta(1) is an important immunomodulator.
Murat SUNGUR, Karakurt, S, Ceyhan, BB, Emel DEMIRALP, Sait KARAKURT, Demiralp, E, Zuha L. KARAKURT, Sungur, MURAT, Karakurt, ZL, Berrin Bagci CEYHAN   +9 more
core   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

The effect of transforming growth factor beta 1 (TGF-beta 1) on the regenerate bone in distraction osteogenesis - A biomechanical, histologic and immunohistochemical study on rabbits

, 2007
Distraction osteogenesis is a well established clinical treatment for limb length dicrepancy and skeletal deformities. Transforming growth factor beta 1 (TGF-beta 1) is a multifunctional peptide which controls proliferation and expression of cells ...
Feyza Unlu Ozkan, OZKAN, Feyza Unlu, Mehmet Turker, OZKAN, Korhan, Levent Eralp, Mehmet Kocaoglu, Melih Guven, SAHIN, Kemal, Türker, Mehmet, GUVEN, Melih, KOCAOGLU, Mehmet, Bilge Bilgic, ERALP, Levent, BILGIC, Bilge, Korhan Ozkan, Kemal Sahin, Bulent Ahishali, Ahishali, Bülent, Zihni Mutlu, Mutlu, Zihni   +19 more
core   +1 more source

The influence of plasma TGF-beta1 levels on development of postradiotherapy fibrosis in breast cancer patients [PDF]

Archive of Oncology, 2002
Mladenović Jasmina, Borojević Nenad D., Todorović-Raković Nataša, Nešković-Konstantinović Zora, Nikolić-Vukosavljević Dragica   +4 more
doaj   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Evaluation of transforming growth factor and vascular endothelial growth factor polymorphisms in Taiwan Chinese patients with pterygium [PDF]

, 2010
[[abstract]]PURPOSE. Pterygium is an invasive and highly vascularized growth, thought to arise from activated and proliferating limbal epithelial stem cells. Epidemiologic studies have found the increase of active angiogenic and epithelial growth factors
Bau, DT (Bau, D. -T.); Chiang, CC (Chiang, C. -C.); Tsai, YY (Tsai, Y. -Y.); Lee, CC (Lee, C. -C.); Tsai, Y (Tsai, Y.); Lin, CC (Lin, C. -C.); Tsai, CH (Tsai, C. -H.); Tsai, FJ (Tsai, F. -J.)
core  

Transforming growth factor-beta inhibits the expression of clock genes

, 2012
Disturbances of sleep-wake rhythms are an important problem in Alzheimer's disease (AD). Circadian rhythms are regulated by clock genes. Transforming growth factor-beta (TGF-β) is overexpressed in neurons in AD and is the only cytokine that is increased ...
Birchler, Thomas, Gietl, Anton, Petrzilka, Saskia, Gast, Heidemarie, Fontana, Adriano, Hock, Christoph, Müller, Andreas, Gordic, Sonja, Lopez, Martin   +8 more
core   +1 more source