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Transfusion-Related Acute Lung Injury
Current Opinion in Hematology, 2000Transfusion-related acute lung injury is a life-threatening complication of hemotherapy associated with the transfusion of plasma-containing blood products. It is characterized by acute respiratory distress, pulmonary edema and hypoxemia. Although its frequency is unknown, Food and Drug Administration data suggest that it is the third most common cause
null Wallis, null Lucas, null Leach
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Transfusion-related acute lung injury
Transfusion Medicine Reviews, 2003Transfusion-related acute lung injury (TRALI) is an uncommon complication of allogeneic blood transfusion manifested typically by shortness of breath, fever, and hypotension. It has been estimated to occur in 0.04% to 0.16% per patient transfused. TRALI has been identified as an important cause of transfusion-related morbidity and mortality.
Kathryn E, Webert, Morris A, Blajchman
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Transfusion-related acute lung injury
Blood Reviews, 2006Transfusion-related acute lung injury (TRALI) is a life-threatening adverse event of transfusion, which has an increasing incidence in the United States and is the leading cause of transfusion-related death. TRALI and acute lung injury (ALI) share a common clinical definition except that TRALI is temporally- and mechanistically-related to transfusion ...
Christopher C, Silliman +1 more
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Transfusion-Related Acute Lung Injury
Anesthesia & Analgesia, 2004Transfusion-related acute lung injury (TRALI) is the leading cause of transfusion-related mortality. It is characterized by injury to the alveolar-capillary membrane precipitated by transfusion factors, antibodies, and/or inflammatory mediators, in a susceptible host. In the absence of a specific test, TRALI is defined clinically as a syndrome of acute
Pearl, Toy, Ognjen, Gajic
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Transfusion-related acute lung injury
Intensive Care Medicine, 1988Noncardiogenic pulmonary edema after transfusion therapy is an infrequent but hazardous complication. The occurrence of this entity is linked to the presence of circulating leukoagglutinins. The clinical features are described on the basis of four cases. The hemodynamic changes, underlying mechanisms and therapeutic strategies are discussed.
Gans, R. O.B. +3 more
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Transfusion‐related acute lung injury
Transfusion, 1993Transfusion-related acute lung injury is a life-threatening complication of hemotherapy associated with the transfusion of plasma-containing blood products. It is characterized by acute respiratory distress, pulmonary edema and hypoxemia. Although its frequency is unknown, Food and Drug Administration data suggest that it is the third most common cause
M A, Popovsky, H C, Chaplin, S B, Moore
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Transfusion Related Acute Lung Injury in a Neonate
The Indian Journal of Pediatrics, 2011Transfusion related acute lung injury (TRALI) is a life threatening and potentially fatal complication of blood component transfusion, which largely remains under- diagnosed and under-reported, especially in neonates. The present case aims to emphasize that TRALI should be kept as a differential diagnosis in all groups of patients, including neonates ...
Shuchita, Gupta +3 more
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Recurrent transfusion‐related acute lung injury
Transfusion, 2001BACKGROUND:Transfusion‐related acute lung injury (TRALI) is a rare condition that is commonly associated with the transfusion of donor plasma containing WBC antibodies. Biologically active lipids that accumulate during storage of RBCs and platelets may also cause TRALI.
N, Win +5 more
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Transfusion-related Acute Lung Injury: An Overview
Current Pharmaceutical Design, 2012This paper will summarize the clinical features of transfusion-related acute lung injury (TRALI) before the experimental and clinical literature on the pathogenesis of TRALI is reviewed. Several mechanisms by which leukocyte antibodies induce TRALI have been unraveled.
Behnaz, Bayat, Ulrich J, Sachs
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