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Transfusion-Related Acute Lung Injury
Current Opinion in Hematology, 2000Transfusion-related acute lung injury is a life-threatening complication of hemotherapy associated with the transfusion of plasma-containing blood products. It is characterized by acute respiratory distress, pulmonary edema and hypoxemia. Although its frequency is unknown, Food and Drug Administration data suggest that it is the third most common cause
null Wallis, null Lucas, null Leach
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Transfusion-related acute lung injury
Blood Reviews, 2006Transfusion-related acute lung injury (TRALI) is a life-threatening adverse event of transfusion, which has an increasing incidence in the United States and is the leading cause of transfusion-related death. TRALI and acute lung injury (ALI) share a common clinical definition except that TRALI is temporally- and mechanistically-related to transfusion ...
Christopher C, Silliman +1 more
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Transfusion‐related acute lung injury
Transfusion, 1993Transfusion-related acute lung injury is a life-threatening complication of hemotherapy associated with the transfusion of plasma-containing blood products. It is characterized by acute respiratory distress, pulmonary edema and hypoxemia. Although its frequency is unknown, Food and Drug Administration data suggest that it is the third most common cause
M A, Popovsky, H C, Chaplin, S B, Moore
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Transfusion-related acute lung injury
Intensive Care Medicine, 1988Noncardiogenic pulmonary edema after transfusion therapy is an infrequent but hazardous complication. The occurrence of this entity is linked to the presence of circulating leukoagglutinins. The clinical features are described on the basis of four cases. The hemodynamic changes, underlying mechanisms and therapeutic strategies are discussed.
Gans, R O +3 more
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Transfusion-Related Acute Lung Injury
Anesthesia & Analgesia, 2004Transfusion-related acute lung injury (TRALI) is the leading cause of transfusion-related mortality. It is characterized by injury to the alveolar-capillary membrane precipitated by transfusion factors, antibodies, and/or inflammatory mediators, in a susceptible host. In the absence of a specific test, TRALI is defined clinically as a syndrome of acute
Pearl, Toy, Ognjen, Gajic
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Transfusion-related acute lung injury
Transfusion Medicine Reviews, 2003Transfusion-related acute lung injury (TRALI) is an uncommon complication of allogeneic blood transfusion manifested typically by shortness of breath, fever, and hypotension. It has been estimated to occur in 0.04% to 0.16% per patient transfused. TRALI has been identified as an important cause of transfusion-related morbidity and mortality.
Kathryn E, Webert, Morris A, Blajchman
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Recurrent transfusion‐related acute lung injury
Transfusion, 2001BACKGROUND:Transfusion‐related acute lung injury (TRALI) is a rare condition that is commonly associated with the transfusion of donor plasma containing WBC antibodies. Biologically active lipids that accumulate during storage of RBCs and platelets may also cause TRALI.
N, Win +5 more
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Severe Transfusion-Related Acute Lung Injury
Anesthesia & Analgesia, 2005A 46-yr-old man developed severe hypoxemia, pulmonary infiltrates, and an acute decrease in his leukocyte count shortly after transfusion of fresh-frozen plasma (FFP) during recovery from cardiac surgery. Cardiogenic pulmonary edema was excluded. Granulocyte-reactive and agglutinating alloantibodies were detected in the serum of the fresh-frozen plasma
Lukas, Brander +5 more
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