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Prevention of transfusion-transmitted infections
Blood, 2019AbstractSince the 1970s, introduction of serological assays targeting virus-specific antibodies and antigens has been effective in identifying blood donations infected with the classic transfusion-transmitted infectious agents (TTIs; hepatitis B virus [HBV], HIV, human T-cell lymphotropic virus types I and II, hepatitis C virus [HCV]).
Michael P. Busch +2 more
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Notification of transfusion transmitted infection
Indian Journal of Medical Ethics, 2008The National Blood Policy of India, 2002, advocates the disclosure of results of transfusion transmitted infections (TTI) to blood donors. However, in the absence of well-defined notification processes, and in order to avoid serious consequences resulting from unguided disclosure, blood bank personnel discard blood that is TTI-positive.
Lincoln P, Choudhury, Shailaja, Tetali
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Transfusion-Transmitted Retrovirus Infection
Hematology/Oncology Clinics of North America, 1995This article reviews the history, classification, and disease associations of the known human retroviruses and outlines their profound effects on the practice of transfusion medicine. The immunodeficiency viruses, HIV-1 and HIV-2, produce a cytolytic effect on infected lymphocytes, and are the causative agents of AIDS.
A E, Williams, M T, Sullivan
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Transfusion-Transmitted Bacterial Infection
Hematology/Oncology Clinics of North America, 1995Transfusion-transmitted bacterial infection is a persistent but often underemphasized problem facing transfusion medicine today. The present status of bacterial contamination of red cells, platelet products and plasma, frequency of contamination, and types of organisms implicated is reviewed.
L A, Krishnan, M E, Brecher
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Transfusion-Transmitted Cytomegalovirus Infection
Hematology/Oncology Clinics of North America, 1995Transfusion-associated cytomegalovirus (CMV) infections is associated with significant morbidity and mortality in immunocompromised seronegative patients. Seronegative blood products reduce the incidence of infection to less than 7%. Filtered blood may be an effective alternative to seronegative blood products for prevention of transfusion-associated ...
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The Risk of Transfusion-Transmitted Infection
New England Journal of Medicine, 1992Four key measures help keep the use of blood safe. First, all who prescribe blood should try to limit the frequency of homologous transfusion by responding only to patients' physiologic needs and b...
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The Continuing Risk of Transfusion-Transmitted Infections
New England Journal of Medicine, 2006An emerging agent can threaten the safety of the blood supply. Drs. Morris Blajchman and Eleftherios Vamvakas write that the risk of transfusion-transmitted infection is not static, as new agents continue to emerge and old ones change their properties and epidemiologic patterns.
Morris A, Blajchman +1 more
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Risks of transfusion-transmitted infections: 2003
Current Opinion in Hematology, 2003While the risks of transfusion-transmitted human immunodeficiency virus, hepatitis C virus, and human T-cell leukemia virus I/II continue to decrease, additional threats to transfusion safety are posed by emerging "new" infectious diseases.Following the introduction of nucleic acid testing for human immunodeficiency virus and hepatitis C virus, the ...
Gregory J, Pomper +2 more
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