Results 131 to 140 of about 4,842,335 (379)

Unusual, non-anaphylactic transfusion reactions associated with severe IgA and IgM deficiencies and anti-IgA [PDF]

, 2021
Denis F. Noubouossie, Marisa B. Marques, Rance C. Siniard, José Lima   +3 more
openalex   +1 more source

Immobilized Enzymes for ABO‐Independent Blood Cell Transfusions

ChemBioChem, EarlyView.
A method is developed to generate universal red blood cells and platelets using suitable glycosidases immobilized to polymethacrylate microparticles. This approach allows the efficient removal of the enzymes converting the A and B antigens before transfusion to avoid immune reactions and illustrates a promising method to counteract the demand for blood
Christina Möller, Fabian Pohlschröder, Jan Wesche, Paula Schmiade, Merle Baselau, Kristian Wende, Berenika Stloukalová, Dominique Böttcher, Andreas Greinacher, Uwe T. Bornscheuer, Henrik Terholsen, Konstanze Aurich   +11 more
wiley   +1 more source

Guideline on the investigation and management of acute transfusion reactions Prepared by the BCSH Blood Transfusion Task Force [PDF]

, 2012
Hazel Tinegate, Janet Birchall, Alexandra Gray, Richard Haggas, Edwin Massey, D. R. Norfolk, Deborah Pinchon, Carrock Sewell, A. W. Wells, Shubha Allard   +9 more
openalex   +1 more source

Human Protein Z as the Second Known Heme‐Binding Protein from the Endogenous Blood Coagulation Inhibitor System

ChemBioChem, EarlyView.
Protein Z is a vitamin K‐dependent anticoagulant with elusive molecular functions. Herein, it is shown that heme binds to protein Z and induces conformational changes. One histidine‐based heme‐binding motif is identified. High heme‐binding affinity and functional effects are demonstrated on protein level. These findings shed new light on the structural
Paula Lindemann, Marie‐T. Hopp
wiley   +1 more source

Clinical Practice Simulation for Blood Transfusion Reactions: An Interprofessional Approach [PDF]

, 2015
Justin R. Rhees, Carolyn H. Scheese, Denise Ward, Lynn Hollister, Takara L. Blamires, Diana G. Wilkins, Connie Madden   +6 more
openalex   +1 more source

Should adding pain, oxygen saturation and physical assessment to vital signs become the new standard of care for detecting blood transfusion reactions? [PDF]

, 2022
Jamie K. Roney, Barbara Erin Whitley, Lauren Johnston, Michella Deleon, Judith Christine Robnett   +4 more
openalex   +1 more source

Synthesis and In Vitro Activity of Hypofuran B and Analogs Against Plasmodium Falciparum and Trypanosoma Cruzi

ChemMedChem, EarlyView.
Hypofuran B, drynaran, and a series of analogs are obtined by crossed aldol condensation from furfural dereivatives. Compunds are tested for in vitro activity agaisnt Trypanosoma cruzi and Plasmodium falciparum. Best results are obtained Against P. falciparum, with IC50 values ranging from 5,35 to 10,35 µg mL−1.
Cristiane Aparecida Franco, Jodieh Oliveira Santana Varejão, Isabela Penna Ceravolo, Victória Miranda Machado, Antoniana Ursine Krettli, Daniela de Melo Resende, Silvane Maria Fonseca Murta, Felipe Terra Martins, Eduardo Jorge Pilau, Vinícius Ribeiro Montes, Markus Kohlhoff, Eduardo V. V. Varejão   +11 more
wiley   +1 more source

Population Pharmacokinetics and Exposure–Response Analyses of Momelotinib, Its Active Metabolite (M21), and Total Active Moiety in Myelofibrosis

Clinical Pharmacology &Therapeutics, EarlyView.
Momelotinib, a Janus kinase (JAK) 1/JAK2/activin A receptor type 1 inhibitor, is approved for the treatment of myelofibrosis with anemia. These analyses characterized the population pharmacokinetics of momelotinib and its active metabolite M21 following administration of the commercial tablet formulation in patients with myelofibrosis from phase II/III
Benjamin Rich, Meenakshi Srinivasan, Yu Liu Ho, Sandra A.G. Visser, Geraldine Ferron‐Brady, Georgios Vlasakakis   +5 more
wiley   +1 more source

Research progress of hyperhemolytic syndrome after transfusion

Zhongguo shuxue zazhi
Hemolytic transfusion reactions after transfusion include acute hemolytic transfusion reaction and delayed hemolytic transfusion reaction. However, clinically, it is observed that after transfusion, the hemoglobin (Hb) level not only fails to increase ...
HE Ziyi
doaj   +1 more source

Rh Negative Status and Isoimmunization Update: A Case-Based Approach to Care [PDF]

, 2003
Prior to the 1970s and the advent of Rho (D) immune globulin (RIG) for Rh negative women, hemolytic disease of the newborn led to morbidity, long-term disabilities, and mortality.
Hanson, Lisa, Harrod, Kathryn Shisler, Heywood, Patricia, VandeVusse, Leona   +3 more
core   +1 more source