Results 61 to 70 of about 6,466 (191)

Transgenerational inheritance of mitochondrial hormetic oxidative stress mediated by histone H3K4me3 and H3K27me3 modifications

Redox Biology
Mitochondrial hormetic oxidative stress (mtHOS) is crucial in physiology and disease; however, its effects on epigenetic inheritance and organism fitness across generations remains elusive. Utilizing the C.
Yimin Li, Chongyang Wang, Xiaoxia Fu, Dan Wu, Chenyang He, Wenyu Dai, Xiaoyang Yue, Zhenhuan Luo, Jing Yang, Qin-Li Wan   +9 more
doaj   +1 more source

Trauma, Testimony and Lower Secondary Holocaust Education in Rywka Lipszyc's and Otto Wolf's Diaries

Children &Society, EarlyView.
ABSTRACT This article examines how Holocaust‐related trauma is represented in two diaries written by Jewish adolescents during the Second World War: Rywka Lipszyc's diary and Otto Wolf's diary. The article combines a thematically guided close reading of the diaries with a didactic discussion of their possible use in lower secondary literary education ...
Milan Mašát
wiley   +1 more source

Developmental Plasticity and Behavioural Evolution in Rodents: Insights From African Striped Mice (Rhabdomys)

Journal of Zoology, EarlyView.
Our review synthesizes how early‐life experiences shape behavioural development in rodents, drawing on developmental plasticity, non‐genetic inheritance and epigenetic mechanisms. Using African striped mice (Rhabdomys) and other small mammal systems as case studies, it presents an integrative framework linking parental care, developmental pathways and ...
N. Pillay, T. L. Rymer
wiley   +1 more source

Predictive evolutionary genomics: principles, validation, and practice

New Phytologist, EarlyView.
Summary Climate change and habitat loss are driving rapid evolutionary responses in populations world‐wide, which creates an urgent need for evolutionary forecasting in conservation and agriculture. Such forecasting can be categorized into three time scales: trait‐based models that use multivariate quantitative genetic equations to project correlated ...
Daniel Ortiz‐Barrientos, Maddie E. James, Yang Liu, Dan Bock, Moisés Exposito‐Alonso, Loren H. Rieseberg   +5 more
wiley   +1 more source

COMPARE Family (Children of Mentally Ill Parents at Risk Evaluation): A Study Protocol for a Preventive Intervention for Children of Mentally Ill Parents (Triple P, Evidence-Based Program That Enhances Parentings Skills, in Addition to Gold-Standard CBT With the Mentally Ill Parent) in a Multicenter RCT—Part II

Frontiers in Psychiatry, 2019
Background: Mental health problems are highly frequent, as well as being associated with enormous societal and economic costs and significant disability-adjusted life years.
Markus Stracke, Kristin Gilbert, Meinhard Kieser, Christina Klose, Johannes Krisam, David D. Ebert, David D. Ebert, Claudia Buntrock, Hanna Christiansen   +8 more
doaj   +1 more source

For colonization success, should hosts and microbes travel alone, together, or swap partners along the way?

New Phytologist, EarlyView.
Experimental co‐introduction of duckweeds (Lemna japonica) and their microbiome in a common pond. Summary Microbiomes that enhance the performance of host plants are likely to be co‐introduced with their host during colonization because of their intimate association.
Takuji Usui, Jingcheng Yu, Megan E. Frederickson   +2 more
wiley   +1 more source

The role of calcium homeostasis dysregulation in allergic rhinitis

Frontiers in Immunology
The global prevalence of allergic rhinitis (AR) continues to rise, imposing a substantial burden on patient quality of life. Its pathogenesis is highly complex, encompassing immune dysregulation, compromised nasal mucosal epithelial barrier function ...
Li Xiao, Kai Chen, Yicheng Wen, Yueqi Fang, Li Tian, Li Tian   +5 more
doaj   +1 more source

Transgeneration transmission of carcinogenic risk [PDF]

Carcinogenesis, 1992
L, Tomatis, S, Narod, H, Yamasaki
openaire   +2 more sources

Beyond Deterministic Fetal Programming: Intrauterine Exposures and the Multifactorial Origins of Adiposity

Obesity Reviews, EarlyView.
ABSTRACT Excess adiposity is not a recently developed problem but has existed since at least the upper Paleolithic, allowing evolutionary selection pressures to adapt the physiology of the pregnant woman and the feto‐placental unit for maternal and fetal protection.
Gernot Desoye, Ursula Hiden, Evelyn Jantscher‐Krenn, Herbert Fluhr, Jonathan C. Wells, Sonja Entringer, Mireille N. M. van Poppel   +6 more
wiley   +1 more source

Transgenerational epigenetic inheritance: resolving uncertainty and evolving biology

Biomolecular Concepts, 2015
Transgenerational epigenetic inheritance in animals has increasingly been reported in recent years. Controversies, however, surround this unconventional mode of heredity, especially in mammals, for several reasons.
Sharma Abhay
doaj   +1 more source