Results 101 to 110 of about 17,611 (257)

Entorhinal Astrocyte Transplants Restore Spatial Exploration and Alleviate Amyloid‐Beta Pathology in Alzheimer's Mice

Advanced Science, EarlyView.
Impaired MEC astrocytic Ca2+ signaling is associated with fragmented spatial exploration in AD mice. Region‐specific glial progenitor transplantation generates engrafted astrocytes that are accompanied by improved AQP4 polarization, reduced amyloid‐β‐associated pathology, attenuated neuroinflammation, preserved synaptic integrity, and ameliorated ...
Fengjuan Wu, Jihua Fan, Xiang Zhou, Zhiqi Yang, Mingyue Gong, Mingzhu Huang, Zhenlu Cai, Shaofan Yang, Teng Teng, Chuanyan Yang, Jin Li, Haoyu Wang, Shuangshuang Dai, Chunhai Chen, Xiaowei Chen, Manxia Wang, Kuan Zhang   +16 more
wiley   +1 more source

Information and characteristics of the primers used in CDS (Coding Domain Sequence) amplification of ScMYBAS1 for functional analysis; insertion of Gateway sites; analysis of expression in transgenic plants; confirmation of transgenics; and estimate the copy number of the transgene.

, 2018
Information and characteristics of the primers used in CDS (Coding Domain Sequence) amplification of ScMYBAS1 for functional analysis; insertion of Gateway sites; analysis of expression in transgenic plants; confirmation of transgenics; and estimate the ...
Michael dos Santos Brito (779421), Silvana Creste (753890), Samira Domingues Carlin (6053522), Maria Helena de Souza Goldman (6053525), Rafael Fávero Peixoto-Junior (6053510), Alexandre Palma Boer Martins (6053519), Paula Macedo Nobile (6053516), Larissa Mara de Andrade (6053513), Rafael Vasconcelos Ribeiro (5912270), Antonio Vargas de Oliveira Figueira (6053531), João Felipe Nebó Carlos de Oliveira (6053528)   +10 more
core   +1 more source

Asymmetric Evolution of Antennal Cell Types Underlies a Derived Ammonia‐Sensing Logic for Ecological Adaptation in Bactrocera dorsalis

Advanced Science, EarlyView.
Comparative antennal single‐nucleus transcriptomics reveals cell‐type‐dependent transcriptomic divergence in Bactrocera dorsalis, with similar structural cells but divergent sensory neurons. This neuronal diversification is associated with a distinct ammonia‐sensing pathway, linking female attraction to bird‐dropping‐associated cues with nutritional ...
Wei Liu, Shuai Zhang, Jie Zhang, Zhen Tian, Yuanbo Xue, Ling Yang, Jun Xu, Guirong Wang   +7 more
wiley   +1 more source

IgG subclasses of TSHR antibodies in Hi- and Lo expressor A-subunit transgenic mice and WT littermates injected with anti-CD25 before immunization with TSHR A-sub protein+CFA and two subsequent injections of human TSHR A-subunit-adenovirus.

, 2013
ELISA plates were coated with TSHR A-subunit protein and serum binding was detected using goat anti-mouse IgG1, IgG2a and IgG2b. Data are shown for the mean+SEM OD 490 nm in ELISA for 4 WT mice, 7 Lo-expressor transgenics and 5 Hi-expressor transgenics.
Sandra M. McLachlan (308347), Chun-Rong Chen (308351), Basil Rapoport (308356), Holly A. Aliesky (308349), Gao Chong (308354)   +4 more
core   +1 more source

Dual‐Organelle Secretome Conjugation and Organ‐Uptake Tracking (DuO‐SCOUT) Enables Deep and Sensitive Mapping of the Secreted Proteins

Advanced Science, EarlyView.
A novel dual‐organelle proximity labeling platform, DuO‐SCOUT, decodes the complex landscape of systemic organ‐organ communication by capturing both classical and unconventional secretomes. Application in metabolic models maps the adipose‐to‐brain secretory relay, identifying selective extra‐hypothalamic sites for adipose‐derived factors and expanding ...
Fenglian Yang, Rui Qian, Jiaxing Song, Xingqi Meng, Jin Young Kim, Kwok On Lai, Li Wang, Liang Zhang   +7 more
wiley   +1 more source

Development of cotton transgenics with antisense AV2 gene for resistance against cotton leaf curl virus (CLCuD) via Agrobacterium tumefaciens

, 2005
Cotton transgenics for resistance against cotton leaf curl disease using antisense movement protein gene (AV2) were developed in an Indian variety (F846) via Agrobacterium-mediated transformation using the protocol developed previously.
Kirthi, N, Maiya, SP, Sanjaya, *, Sita, Lakshmi G, Savithri, HS, Prasad, V, Satyavathi, VV   +6 more
core   +2 more sources

Southern and northern blot analyses of putative ICMP 451- BjNPR1 transgenics of pearl millet in T₀ generation.

, 2014
(A) Southern blot of BglII digested genomic DNA probed with BjNPR1 sequence showing hybridized bands of >3.0 kbp. (B) Northern blot probed with BjNPR1 internal sequence showing hybridizable bands of ∼2 kb. Lane UC: Untransformed ICMP 451.
Ramadevi Ramineni (531678), Vijayakumar Sadumpati (531679), Dashavantha Reddy Vudem (454224), Venkateswara Rao Khareedu (454225)   +3 more
core   +1 more source

The BTB/POZ‐MATH Protein ZmBPM1 Interacts With Autophagy‐related Protein ZmATG6 and Modulates the NLR Protein Rp1‐D21‐Mediated Defense Response in Maize

Advanced Science, EarlyView.
The maize BTB/POZ‐MATH (BPM) protein ZmBPM1 interacts with autophagy‐related protein ZmATG6 to relocate the NLR protein Rp1‐D21 from the nucleo‐cytoplasmic compartment into autophagosome‐like puncta, leading to autophagy‐mediated turnover and suppressing the hypersensitive response.
Chang‐Xiao Tang, Tong‐Tong Liu, Qi‐Dong Ge, Xiao‐Ying Liu, Wanxiao Wang, Yang Sun, Yanfei Liu, Faqiang Li, Guan‐Feng Wang   +8 more
wiley   +1 more source

Kidney cysts in double transgenics can be found throughout all segments of the nephron.

, 2013
(A–D) H&E staining of adult kidneys demonstrates numerous cystic dilatations in the cortex and outer medulla in Six2-cretg/+, Wnt9btg/+ double transgenics and a normal kidney architecture in Wnt9btg/+ controls.
Lynn Robbins (311068), Michael Rauchman (311070), Susan M. Kiefer (311067)   +2 more
core   +1 more source

Drought Stress Mediated Changes in Food Crops: Mechanisms and Remediation Strategies

Advanced Science, EarlyView.
This work presents a multi‐scale framework for flavonoid‐mediated drought tolerance in staple food crops, integrating ROS redox regulation, antioxidant defense, rhizosphere microbial interactions, and sustainable agronomic practices. This interdisciplinary model provides core insights to develop climate‐resilient cropping systems and enhance global ...
Xiaoyi Duan, Litao Wang, Tuuli‐Marjaana Koski, Lizhe An, Thomas Efferth, Yujie Fu   +5 more
wiley   +1 more source