Persistent Dizziness and Time-Domain Dissociation in Vestibular Function: A Hypothesis-Generating Case Series and Spatiotemporal Framework for Targeted Vestibular Rehabilitation. [PDF]
Healthcare (Basel)Manzari L, Manzari MS.
europepmc +1 more source
FEBS Open Bio, EarlyView.5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley +1 more source
Enforced BATF expression via clinically approved LNPs enhances adoptive T-cell therapies. [PDF]
Blood SciGe H +8 more
europepmc +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
Distinguishing Detectable From Clinically Relevant Immunogenicity With Subcutaneous Infliximab. [PDF]
United European Gastroenterol JLu MY, Shu YP, Shi R.
europepmc +1 more source
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
Early Renal Microcirculatory Perfusion Patterns in Sepsis: Associations with SA-AKI Trajectories in the Emergency Department. [PDF]
Diagnostics (Basel)Gökçimen M, Akçay G, Sönmez BM.
europepmc +1 more source
FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
A totally laparoscopic strategy combining microwave ablation and autologous blood transfusion for patients with initial WSES grade IV traumatic splenic rupture in selected transient responders: a proof-of-concept study. [PDF]
Eur J Trauma Emerg SurgFeng Z, Xie D, Hong W, Zheng C.
europepmc +1 more source