Results 21 to 30 of about 23,060 (253)

Digital governance mechanisms and principles that enable agile responses in dynamic competitive environments

open access: yes, 2022
Being an agile company today is no longer just about timely recognition of early signs of change in order to defend an existing competitive position but rather being able to perpetually transition between a series of short-lived, temporary competitive ...
DARIA ARKHIPOVA   +2 more
core   +1 more source

Colloidal Plasmonic Nanoparticles for Ultrafast Optical Switching and Laser Pulse Generation

open access: yesFrontiers in Materials, 2018
Light-matter interactions are greatly enhanced and spatially well-confined in plasmonic nanostructures in the spectral resonance range. In colloidal plasmonic nanoparticle (NP), this effect is manifested by the strong absorption caused by the collective ...
Xiaofeng Liu
doaj   +1 more source

持続的な競争優位のマネジメント再考

open access: yes, 2017
2017-03-25The purpose of this paper is to rethink about the management of sustainable competitive advantage. Historically, sustainable competitive advantage was main issue in strategic management and numerous studies treated of this topics.
山田, 基成, YAMADA, Moronari
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

L-serine promotes pro-carcinogenic effects of colibactin-producing E. coli

open access: yesGut Microbes
Colonic tissues are abnormally colonized by colibactin-producing Escherichia coli (CoPEC) in colorectal cancer (CRC) patients. CoPECs have been shown to promote colorectal carcinogenesis in several pre-clinical CRC mouse models.
Amandine Devaux   +10 more
doaj   +1 more source

Extinction Debt and Colonizer Credit on a Habitat Perturbed Fishing Bank.

open access: yesPLoS ONE, 2016
Temporal changes in occupancy of the Georges Bank (NE USA) fish and invertebrate community were examined and interpreted in the context of systems ecological theory of extinction debt (EDT). EDT posits that in a closed system with a mix of competitor and
Daniel E Duplisea   +2 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Effect of Innovative Capabilities on Transient Competitive Advantage among Hospitals in Kenya

open access: yesThe University Journal
This paper examined the effect of innovative capabilities on transient competitive advantages of private hospitals in Kenya. The study addresses the competitive challenges faced by private hospitals in Kenya targeting 476 private hospitals’ top managers. The findings presented in this paper were drawn from 209 hospital managers.
Evalyne Khamasi Amboyi   +2 more
openaire   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

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