MECHANISMS IN ENDOCRINOLOGY: The pathophysiology of transient congenital hypothyroidism. [PDF]
Eur J Endocrinol, 2022 Abstract Transient congenital hypothyroidism (TCH) refers to congenital hypothyroidism which spontaneously resolves in the first few months or years of life. Currently, there is a paucity of reliable markers predicting TCH at diagnosis, and the diagnosis is established following the withdrawal of levothyroxine therapy around 3 years of ...
Peters C, Schoenmakers N.
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Etiological Evaluation of Congenital Hypothyroidism Cases
Journal of Behçet Uz Children's Hospital, 2020 INTRODUCTION: The aim of this study was to determine, (i) the cause of congenital hypothyroidism (permanent or transient), (ii) the etiological cause of persistent congenital hypothyroidism and (iii) to investigate the role of clinical and laboratory ...
Ayşe Anık +3 more
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Changes of antithroglobulin antibody in children with congenital hypothyroidism [PDF]
Annals of Pediatric Endocrinology & Metabolism, 2013 PurposeIt has been reported that antithroglobulin (anti-TG) antibody is increased in the sera of both children with transient congenital hypothyroidism and their mothers.
Eun Mi Cho +3 more
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Predictors of transient congenital primary hypothyroidism: data from the German registry for congenital hypothyroidism (AQUAPE “HypoDok”) [PDF]
European Journal of Pediatrics, 2021 Abstract Neonatal screening for congenital primary hypothyroidism (CH) may not distinguish between transient (TCH) and permanent dysfunction (PCH), causing potential overtreatment and concerns in affected families. To specify the indication for interruption of therapy, we analysed the German registry “HypoDok” for
Nicola Matejek +9 more
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Prevalence of Transient Hypothyroidism in Children Diagnosed with Congenital Hypothyroidism between 2000 and 2016 [PDF]
International Journal of Molecular Sciences, 2023 Newborn screening (NBS) for congenital hypothyroidism (CH) was introduced in Switzerland in 1977, which allowed for the preclinical, biochemical diagnosis. The aim of this study was to evaluate the prevalence of transient CH (tCH) in the canton of Zurich.
Gmür, Sabrina +2 more
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Prediction of Transient or Permanent Congenital Hypothyroidism
Journal of Pediatric Research, 2022 Aim:Congenital hypothyroidism (CH) is one of the most common endocrinological problems in the neonatal period. CH, which occurs in 1:3,000-4,000 births, is a preventable cause of mental retardation.
Ferda Evin +7 more
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A Case of Congenital Central Hypothyroidism Caused by a Novel Variant (Gln1255Ter) in IGSF1 Gene [PDF]
JCRPE, 2021 Loss-of-function mutations in the immunoglobulin superfamily, member 1 (IGSF1) gene cause X-linked central hypothyroidism, and therefore its mutation affects mainly males.
Doğa Türkkahraman +2 more
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Mìžnarodnij Endokrinologìčnij Žurnal, 2013 The estimation of the level of neuropsychological development has been carried out in 80 children who had laboratory signs of neonatal hypothyroidism (TSH level in blood exceed 20 mIU/L).
Sh.U. Akhmedova
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Prevalence of Sensorineural Hearing Loss in Patients with Congenital Hypothyroidism in Qazvin, Iran (2015) [PDF]
Iranian Journal of Neonatology, 2018 Background: Congenital hypothyroidism increases the risk of sensorineural hearing loss (SNHL). Children with hearing impairment are prone to communication disorders.
Fatemeh Saffari +5 more
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Transient congenital hypothyroidism - too short to be transient. [PDF]
J Postgrad Med, 2021 Congenital hypothyroidism (CH) occurs due to thyroid dysgenesis, thyroid ectopy, and dyshormonogenesis. A proportion of CH is transient which might be due to iodine deficiency/excess or maternal antibody-mediated. Certain forms of dyshormonogenetic defects may cause transient hypothyroidism. Here is a report of a neonate with overt
Subramaniam K.
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