Results 121 to 130 of about 1,147,249 (305)
, 2008 Linear stability and the non-modal transient energy growth in compressible plane Couette flow are investigated for two prototype mean flows: (a) the {\it uniform shear} flow with constant viscosity, and (b) the {\it non-uniform shear} flow with {\it ...
A. Bottaro +8 more
core +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
EnergiesUtilizing the discrete fracture model (DFM), a transient flow model is established for fractured horizontal wells in tight oil reservoirs, accounting for threshold pressure gradient (TPG), stress sensitivity effect, hydraulic fracture parameters, and ...
Lichun Sun +4 more
doaj +1 more source
Homologous expression and purification of human HAX‐1 for structural studies
FEBS Open Bio, EarlyView.This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley +1 more source
NUMERICAL SIMULATION OF TRANSIENT FLOW IN STORM SEWERS USING STANDARD AND IMPROVED MCCORMACK SCHEME
TASK Quarterly, 2012 This paper describes the results of the first part of the research project which aims at developing a hydraulic model for simulation of unsteady flows in storm sewers ranging from gravity flows to surcharged flows resulting with water outflow on the ...
MICHAŁ SZYDŁOWSKI +1 more
doaj
FEBS Open Bio, EarlyView.Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley +1 more source
AtmosphereEvaluating ventilation behavior inside classrooms in hot climates is fundamental to ensure good indoor air quality and proper thermal comfort, thus guaranteeing a healthy environment for the users.
Enrique Cruz-Octaviano +3 more
doaj +1 more source
Travelling perturbations in sheared flows: sudden transition infrequency and phase speed asymptotics [PDF]
, 2012 We present recent findings concerning angular frequency discontinuities in the transient evolution of three-dimensional perturbations in two sheared ows, the plane channel and the wake ows.
De Santi, Francesca +2 more
core
Autophagosome marker, LC3, is released extracellularly via several distinct pathways
FEBS Open Bio, EarlyView.This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito +3 more
wiley +1 more source
EnergiesThe transient operation of pump turbines generates significant flow-induced instabilities, prompting a comprehensive numerical investigation using the SST k−ω turbulence model to examine these instability effects throughout the complete operating range ...
Hongqiang Tang +4 more
doaj +1 more source